Introduction: Due to an increasing demand for the initiation and control of non-invasive ventilation (NIV), digital algorithms are suggested to support therapeutic decisions and workflows in an ambulatory setting. The DIGIVENT project established and implemented such algorithms for patients with chronic hypercapnic respiratory failure due to chronic obstructive pulmonary disease (COPD) by a predefined process.
Methods: Based on long-term clinical experience and guideline recommendations as provided by the German Respiratory Society, detailed graphical descriptions of how to perform NIV in stable COPD patients were created. Subsequently, these clinical workflows were implemented in the Business Process Model and Notation (BPMN) as one tool to formalize these workflows serving as input for an executable digital implementation.
Results: We succeeded in creating an executable digital implementation that reflects clinical decision-making and workflows in digital algorithms. Furthermore, we built a user-friendly graphical interface that allows easy interaction with the DIGIVENT support algorithms.
Conclusion: The DIGIVENT project established digital treatment algorithms and implemented a decision- and workflow-support system for NIV whose validation in a clinical cohort is planned.
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http://dx.doi.org/10.1177/20406223221099338 | DOI Listing |
JCO Oncol Pract
November 2024
U.S. Food and Drug Administration, Silver Spring, MD.
This paper discusses the administrative aspects of molecular diagnostics in oncology, including US Food and Drug Administration (FDA) oversight, the regulatory approval process, clinical, and operational workflows, and payment models. Comprehensive molecular testing is important to deliver optimal oncology care and improve patient outcomes. Despite the potential benefits of testing, utilization remains low.
View Article and Find Full Text PDFKidney Int Rep
August 2024
Division of Nephrology, Department of Medicine, Columbia University, New York, USA.
Yearb Med Inform
August 2022
Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, UT, USA.
Objectives: To review current studies about designing and implementing clinician-facing clinical decision support (CDS) integrated or interoperable with an electronic health record (EHR) to improve health care for populations facing disparities.
Methods: We searched PubMed to identify studies published between January 1, 2011 and October 22, 2021 about clinician-facing CDS integrated or interoperable with an EHR. We screened abstracts and titles and extracted study data from articles using a protocol developed by team consensus.
J Biomed Inform
December 2022
Innovation Center Computer Assisted Surgery (ICCAS), Faculty of Medicine, Leipzig University, Semmelweisstraße 14, 04103 Leipzig, Germany.
Background: Surgical context-aware systems can adapt to the current situation in the operating room and thus provide computer-aided assistance functionalities and intraoperative decision-support. To interact with the surgical team perceptively and assist the surgical process, the system needs to monitor the intraoperative activities, understand the current situation in the operating room at any time, and anticipate the following possible situations.
Methods: A structured representation of surgical process knowledge is a prerequisite for any applications in the intelligent operating room.
Ther Adv Chronic Dis
May 2022
Department of Pulmonology and Intensive Care Medicine, University Hospital Aachen, Aachen, Germany.
Introduction: Due to an increasing demand for the initiation and control of non-invasive ventilation (NIV), digital algorithms are suggested to support therapeutic decisions and workflows in an ambulatory setting. The DIGIVENT project established and implemented such algorithms for patients with chronic hypercapnic respiratory failure due to chronic obstructive pulmonary disease (COPD) by a predefined process.
Methods: Based on long-term clinical experience and guideline recommendations as provided by the German Respiratory Society, detailed graphical descriptions of how to perform NIV in stable COPD patients were created.
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