AI Article Synopsis

  • Recent research shows that the immune system is involved in more than just fighting infections; it also influences various bodily functions even in the absence of pathogens.
  • There is a significant connection between immunity and metabolism, where immune signals can impact metabolic processes and vice versa.
  • The review aims to summarize these findings on how immunity and metabolism interact and explore the underlying biological principles of this relationship.

Article Abstract

Recent studies have revealed that the immune system plays a critical role in various physiological processes beyond its classical pathogen control activity. Even under a sterile condition, various cells and tissues can utilize the immune system to meet a specific demand for proper physiological functions. Particularly, a strong link between immunity and metabolism has been identified. Studies have identified the reciprocal regulation between these two systems. For example, immune signals can regulate metabolism, and metabolism (cellular or systemic) can regulate immunity. In this review, we will summarize recent findings on this reciprocal regulation between immunity and metabolism, and discuss potential biological rules behind this interaction with integrative perspectives. [BMB Reports 2022; 55(6): 259-266].

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252895PMC
http://dx.doi.org/10.5483/BMBRep.2022.55.6.064DOI Listing

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