Time-gated reflection matrix (RM) has been successfully used for optical imaging deep inside scattering media. Recently, this method was extended to enhance the spatiotemporal focusing of light ultra-deep inside scattering media. This is achieved by calibrating the decomposition of the RM with the Tikhonov regularization parameter to convert multiply scattered photons that share the same time of flight with the singly scattered photons into singly scattered photons. Such a capability suggests a reshaping to the interaction mechanism between light and scattering media, which may benefit or inspire wide optical applications that desire enhanced spatiotemporal focusing of light at depths inside scattering media.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160227PMC
http://dx.doi.org/10.1038/s41377-022-00858-wDOI Listing

Publication Analysis

Top Keywords

scattering media
20
inside scattering
16
spatiotemporal focusing
12
focusing light
12
scattered photons
12
deep inside
8
time-gated reflection
8
reflection matrix
8
singly scattered
8
scattering
5

Similar Publications

This study aims to explore the development of natural bio-based amphiphilic block copolymers for drug delivery applications. We investigated block copolymers derived from tamarind seed xyloglucan and solanesol, focusing on their synthesis, structural analysis, aqueous self-assembly, and drug encapsulation. Specifically, xyloglucan hydrolysate segments with number-average degrees of polymerization (DPs) of between 8 and 44 (XOS, XMS, XMS, XMS, and XMS) were used as the hydrophilic blocks, whereas plant-sourced solanesol was selected as the hydrophobic segment.

View Article and Find Full Text PDF

Effective bulk and mass densities of randomly distributed coated cylinders in fluid.

J Acoust Soc Am

January 2025

Laboratoire Ondes et Milieux Complexes LOMC UMR CNRS 6294, Université Le Havre Normandie, 75 rue Bellot, Le Havre, France.

Inhomogeneous media made of random configurations of coated circular cylinders are considered. The effective properties-wave number, mass density, bulk modulus-are discussed and illustrated. The effects of the volume fraction of the scatterers and surrounding fluid are also examined.

View Article and Find Full Text PDF

Genetically engineered immune cells hold great promise for treating immune-related diseases, but their development is hindered by technical challenges, primarily related to nucleic acid delivery. Polyethylenimine (PEI) is a cost-effective transfection agent, yet it requires significant optimization for effective T cell transfection. In this study, we comprehensively fine-tuned the characteristics of PEI/DNA nanoparticles, culture conditions, cellular physiology, and transfection protocols to enhance gene delivery into T cells.

View Article and Find Full Text PDF

Background: Intraoperative imaging is critical for achieving precise cancer resection. Among available techniques, Raman spectral imaging emerges as a promising modality due to its high spatial resolution and signal stability. However, its clinical application for in vivo imaging is limited by the inherently weak Raman scattering signal.

View Article and Find Full Text PDF

Hypothesis: The oil phase controls the persistence length and aqueous channel diameter of reverse wormlike micelles (RWLMs), specifically by tuning the cohesive energy density of alkanes.

Experiments: We explore the influence of alkanes with varying chain lengths on the rheological properties, structural parameters, and morphology of RWLMs. To establish a link between the solvent characteristics and the structure of RWLMs, we employ a diverse set of complementary techniques, including rheological analysis, small-angle X-ray scattering (SAXS), Fourier-transform infrared (FT-IR) spectroscopy, and cryogenic transmission electron microscopy (cryo-TEM).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!