A Caucasian female patient in her 90s was referred to the department of plastic and reconstructive surgery for surgical removal of a large invasive squamous cell carcinoma on the anterior chest wall. A skin biopsy prior to the referral indicated that the tumour was moderately differentiated. The patient suffered from severe congestive heart failure with a mechanical valve prosthesis and atrial fibrillation, and was therefore treated with anticoagulants. Hence, a surgical procedure would be hazardous. Therefore, other treatment options were considered. The principal aim was to reduce the amount of tumour tissue to an appropriate size suitable for later excision with primary wound closure. After interdisciplinary discussions, curettage and electrodessication combined with photodynamic therapy was judged the best alternative treatment in this case. At the 1.5 years follow-up after the intervention there was no indication for further surgery. The patient was at that stage content with the treatment and its outcome.
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http://dx.doi.org/10.1136/bcr-2021-248588 | DOI Listing |
Arch Dermatol Res
January 2025
Department of Dermatology, University of California, Irvine, CA, USA.
J Cosmet Dermatol
December 2024
Consultant Dermatologist, Aalborg University, Aalborg, Denmark.
Objective: We aimed to document the treatment outcomes of African patients treated with low-intensity electrodesiccation for DPN's. Other treatment options for DPN's include snip excision, light curettage, cryotherapy, and lasers devices such as PDL, Nd: YAG, KTP, and CO2, which are generally unsafe for darker skin types and come with high costs.
Methods: Nonprobability convenience sampling of patient records was used to extract retrospective data on demographics and treatment outcomes according to the inclusion criteria.
J Clin Med
September 2024
Department of Dermatology, "Iuliu Hațieganu" University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.
Basal cell carcinoma (BCC) is the most frequent of all cancers, with an increasing incidence. The first line therapy is surgical excision, but topical therapies can be used in low-risk superficial BCCs, while the more advanced, unresectable, or metastatic BCCs benefit from systemic therapies with hedgehog inhibitors and immunotherapy. The purpose of this review is to highlight local and systemic immunotherapies and their efficacy in the management of BCCs.
View Article and Find Full Text PDFArch Dermatol Res
October 2024
, 121 E 60 St, 2D, New York, NY, 10022, USA.
Keratinocyte carcinoma is the most common form of cancer in the United States. Often treated by surgical excision, electrodessication and curettage, or Mohs surgery, treatment can frequently leave patients with a scar and can be time consuming and inconvenient for both patients and healthcare providers. Utilizing non-ablative fractional laser therapy followed by tirbanibulin ointment, we treated 30 basal and/or squamous cell carcinomas on 23 patients over the age of 50 with varying skin types.
View Article and Find Full Text PDFInt J Dermatol
October 2024
Department of Dermatology, LSU Health Sciences Center-New Orleans School of Medicine, New Orleans, LA, USA.
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