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Doctors as Device Manufacturers? Regulation of Clinician-Generated Innovation in the ICU.
Crit Care Med
December 2024
Division of Neurocritical Care, Massachusetts General Hospital, Boston, MA.
Critical care physicians are rich sources of innovation, developing new diagnostic, prognostic, and treatment tools they deploy in clinical practice, including novel software-based tools. Many of these tools are validated and promise to actively help patients, but physicians may be unlikely to distribute, implement, or share them with other centers noncommercially because of unsettled ethical, regulatory, or medicolegal concerns. This Viewpoint explores the potential barriers and risks critical care physicians face in disseminating device-related innovations for noncommercial purposes and proposes a framework for risk-based evaluation to foster clear pathways to safeguard equitable patient access and responsible implementation of clinician-generated technological innovations in critical care.
View Article and Find Full Text PDFA case report of exacerbation of extrapyramidal symptoms following the switch from risperidone to paliperidone during valproate therapy.
BMC Psychiatry
January 2025
Department of Psychiatry, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-Ku, Yokohama, Kanagawa, 236-0004, Japan.
Background: Paliperidone is a second-generation antipsychotic and the main active metabolite of risperidone, formulated to provide consistent therapeutic effects through an extended-release system, designed to provide consistent therapeutic effects through an extended-release formulation. While commonly used in clinical practice, switching from risperidone to paliperidone, particularly during valproate therapy, can pose challenges due to potential pharmacokinetic interactions that may increase the risk of extrapyramidal symptoms (EPS). Despite clinical observations suggesting these interactions, case reports documenting such adverse effects are scarce.
View Article and Find Full Text PDFEnhancing public sector employees ' professional identity: A study using China's Labor Force Survey data.
PLoS One
January 2025
School of Economics and Management, Inner Mongolia Normal University, Inner Mongolia, China.
Public sector employees, as the crucial link between the party, government, and the general public, represent the frontline in safeguarding the interests of the people and providing services to them. They profoundly influence the implementation and execution of national policy directives. Using data from China's Labor Force Survey and employing a combination of exploratory factor analysis and confirmatory factor analysis, this research constructs an evaluation index system for public sector employees' Professional Identity.
View Article and Find Full Text PDF[Expert consensus on ethical requirements for artificial intelligence (AI) processing medical data].
Sheng Li Xue Bao
December 2024
Virtual Simulation and Artificial Intelligence Committee, Chinese Association for Physiological Sciences.
As artificial intelligence technology rapidly advances, its deployment within the medical sector presents substantial ethical challenges. Consequently, it becomes crucial to create a standardized, transparent, and secure framework for processing medical data. This includes setting the ethical boundaries for medical artificial intelligence and safeguarding both patient rights and data integrity.
View Article and Find Full Text PDFDevelopment of a pandemic-related core set of quality indicators for quality and patient safety in University Hospitals in Germany.
BMC Health Serv Res
January 2025
Institute for Health Services Research and Clinical Epidemiology, Faculty of Medicine, Philipps-University Marburg, Marburg, Germany.
Background: The COVID-19 pandemic entailed a global health crisis, significantly affecting medical service delivery in Germany as well as elsewhere. While intensive care capacities were overloaded by COVID cases, not only elective cases but also non-COVID cases requiring urgent treatment unexpectedly decreased, potentially leading to a deterioration in health outcomes. However, these developments were only uncovered retrospectively.
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