AI Article Synopsis
- Decreased activities of daily living (ADL) increase the risk of cardiovascular disease and are linked to lower rates of PCI implementation and higher mortality in acute myocardial infarction (AMI) patients.
- Patients were analyzed in three groups based on ADL impairment, revealing that older individuals with impaired ADL had worse outcomes, including higher acute mortality and less likelihood of receiving PCI.
- The study concluded that impaired ADL is an independent risk factor for both short- and long-term mortality in AMI patients, highlighting its significance in clinical assessments and interventions.
Article Abstract
Background: A decrease in the activities of daily living (ADL) is an independent risk factor for cardiovascular disease. Although percutaneous coronary intervention (PCI) is known to prevent early mortality in patients with acute myocardial infarction (AMI), the relationship between ADL prior to myocardial infarction (MI), PCI implementation, and mortality in patients with AMI remains unknown. We investigated the impact of prehospital ADL on PCI implementation and on short- and long-term mortality in patients with AMI.
Methods: We investigated the prehospital ADL in 1479 patients with AMI using data from the Yamagata AMI registry (period: 2015-2017). The patients were divided into three groups (preserved ADL, mildly impaired ADL, and severely impaired ADL) and their clinical characteristics were compared. Multivariate regression analysis was performed to elucidate the association of ADL prior to MI with the PCI implementation and mortality in patients with AMI.
Results: Patients with impaired ADL were older, more likely to be female, less likely to have undergone PCI, and presented with higher acute mortality compared to those with preserved ADL. The proportion of patients with impaired ADL increased with age. Multivariate regression analysis showed that the lack of PCI implementation and prehospital ADL impairment were independent risk factors for acute death in patients with AMI after adjusting for confounding factors. Furthermore, univariate and multivariate analyses revealed that impaired ADL was associated with the PCI implementation. Cox proportional hazards analysis revealed that prehospital ADL impairment was an independent risk factor for long-term mortality in patients with AMI.
Conclusions: Decreased levels of prehospital ADL were associated with lower PCI implementation and higher mortality in patients-especially older patients-with AMI.
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| http://dx.doi.org/10.1016/j.jjcc.2022.05.002 | DOI Listing |
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