AI Article Synopsis
Article Abstract
Anthropogenic organofluorine compounds are recalcitrant, globally distributed, and a human health concern. Although rare, natural processes synthesize fluorinated compounds, and some bacteria have evolved mechanisms to metabolize organofluorine compounds. sp. strain 273 grows with 1-fluorodecane (FD) and 1,10-difluorodecane (DFD) as carbon sources, but inorganic fluoride release was not stoichiometric. Metabolome studies revealed that this bacterium produces fluorinated anabolites and phospholipids. Mass spectrometric fatty acid profiling detected fluorinated long-chain (i.e., C-C) fatty acids in strain 273 cells grown with FD or DFD, and lipidomic profiling determined that 7.5 ± 0.2 and 82.0 ± 1.0% of the total phospholipids in strain 273 grown with FD or DFD, respectively, were fluorinated. The detection of the fluorinated metabolites and macromolecules represents a heretofore unrecognized sink for organofluorine, an observation with consequences for the environmental fate and transport of fluorinated aliphatic compounds.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.est.2c01454 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Exploring the gut-brain axis in alzheimer's disease treatment via probiotics: evidence from animal studies-a systematic review and meta-analysis.
BMC Neurol
December 2024
Center of Excellence in Nanomedicine, Department of Anatomy, Faculty of Medicine, Chulalongkorn University, 1873 Rama 4 Road, Pathumwan, Bangkok, 10330, Thailand.
Introduction: Alzheimer's disease (AD) is a prevalent neurodegenerative disorder in the elderly, causing cognitive impairment. Its pathogenesis is characterized by amyloid beta deposition, neurofibrillary tangles, and neuroinflammation. Recent research has identified the link between gut dysbiosis, an imbalance of intestinal microorganisms, to this pathogenesis via the gut-brain axis.
View Article and Find Full Text PDFThe alleviation of Cr(Ⅵ) stress on simultaneous nitrification and denitrification process of Acinetobacter haemolyticus RH19.
Water Res
December 2024
The Key Lab of Pollution Control and Ecosystem Restoration in Industry Clusters, Ministry of Education, School of Environment and Energy, South China University of Technology, Guangzhou Higher Education Mega Centre, Guangzhou 510006, PR China. Electronic address:
Bioremediation of Cr(Ⅵ) and ammonia is considered as a promising and cost-effective alternative to chemical and physical methods. However, Cr(Ⅵ) could inhibit nitrogen removal by inhibiting intra-/extracellular electron (IET/EET) transfer or nitrifying and denitrifying enzymes activity due to its higher solubility. In this study, we isolated a simultaneous nitrification and denitrification (SND) microorganism Acinetobacter haemolyticus RH19, capable of outcompeting oxygen to take nitrogen oxides/ammonia as electron acceptors, and studied a combined accelerant (cysteine, biotin and cytokinin) to relive the Cr(Ⅵ) stress.
View Article and Find Full Text PDFPrevalence and antimicrobial resistance of highly virulent cagA-positive Helicobacter pylori strains in Southern Poland.
Eur J Clin Microbiol Infect Dis
December 2024
Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, Krakow, 30-688, Poland.
Purpose: Assessment of Helicobacter pylori (H. pylori) prevalence in Southern Poland, focusing on highly virulent cagA-positive strains associated with gastric cancer risk, along with analysis of antimicrobial resistance and its molecular mechanisms.
Methods: A total of 130 dyspeptic patients, who underwent endoscopy, were enrolled in the study.
Efficient Expression of Oropouche Virus Nonstructural Proteins NSs and NSm.
Methods Mol Biol
December 2024
Department of Pathology, The Sealy Institute for Vaccine Sciences, The Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch at Galveston, Galveston, TX, USA.
Oropouche fever, a mosquito- or midge-borne emerging zoonotic disease endemic to South and Central America, manifests as a dengue-like acute febrile illness with occasional occurrences of meningitis or meningoencephalitis. The causative agent, Oropouche virus (OROV), belongs to the genus Orthobunyavirus within the family Peribunyaviridae. Its tripartite negative-sense RNA genome comprises small (S), medium (M), and large (L) segments, encoding structural N, Gn/Gc, and L proteins, respectively.
View Article and Find Full Text PDFPrevalence and features of hypervirulent in respiratory specimens at a US hospital system.
Infect Immun
December 2024
Center for Innovative Antimicrobial Therapy, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Article Synopsis
- Hypervirulent Klebsiella pneumoniae (hvKp) strains, once thought rare in the U.S., are being increasingly reported, with a study analyzing 273 respiratory isolates from patients in Western Pennsylvania between 2020 and 2022.
- Among these, 13 (4.8%) tested positive for hypervirulent traits, with 2 strains (0.7%) confirmed to carry specific virulence genes, suggesting they can cause severe infections in the community.
- Experiments showed these hvKp strains caused significant pneumonia in mice, indicating their potential to circulate in North America and cause severe community-associated infections.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!