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Study of Carbamoyl Fluoride: Synthesis, Properties and Applications. | LitMetric

Study of Carbamoyl Fluoride: Synthesis, Properties and Applications.

Chemistry

Institute of Chemistry and Biochemistry (ICBMS-UMR CNRS 5246), Univ Lyon, CNRS, Université Lyon 1, 1 rue Victor Grignard, 69622, Lyon, France.

Published: August 2022

Carbamoyl fluoride is a fluorinated group that, to this date, remains underexplored, probably due to the lack of data concerning its properties. In this paper, a study of carbamoyl fluoride is presented. Stability studies, in particular under physiological conditions, and lipophilicity measurement were performed. A new easy, safe, inexpensive, and metal-free synthesis method is also described. Finally, a potential use in radiochemistry through a F/ F isotopic exchange is demonstrated.

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Source
http://dx.doi.org/10.1002/chem.202201589DOI Listing

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