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Towards a Crisis Management Playbook: Hospice and Palliative Team Members' Views Amid COVID-19.
J Pain Symptom Manage
December 2024
Icahn School of Medicine at Mount Sinai (J.B., E.F., P.K., M.D.A.), New York, New York, USA; Geriatric Research, Education and Clinical Center (E.F., M.D.A.), James J. Peters VA Medical Center, Bronx New York, USA.
Context: The critical role of hospice and palliative care in response to the COVID-19 pandemic is well recognized, but there is limited evidence to guide healthcare leadership through future crises.
Objectives: Our goal was to support future organizational resilience by exploring hospice and palliative team members' perspectives on crisis leadership during the COVID-19 pandemic in New York City (NYC).
Methods: This qualitative descriptive study used individual, semi-structured interviews of purposively sampled interdisciplinary team members.
Venetoclax Combined With FLAG-IDA in Refractory or Relapsed Acute Myeloid Leukemia.
Eur J Haematol
January 2025
University Clinic for Hematology, Oncology, Hemostaseology and Palliative Care, Johannes Wesling Medical Center Minden, University of Bochum, Minden, Germany.
Introduction: The prognosis of patients with refractory or relapsed AML (R/R-AML) is very limited. To (re)achieve complete remission, there has recently been increasing evidence that the combination of venetoclax (VEN) with chemotherapy is associated with improved outcomes.
Patients And Methods: Our retrospective, single-center study of 53 R/R-AML patients with a median follow-up time of 11.
Sphingosine 1-phosphate protective effect on human proximal tubule cells submitted to an in vitro ischemia model: the role of JAK2/STAT3.
J Physiol Biochem
November 2024
Laboratório de Biomembranas, Instituto de Biofísica Carlos Chagas Filho - Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Article Synopsis
- * Understanding the underlying mechanisms of AKI is crucial for developing effective treatments, particularly focusing on cell rescue and paracrine factors that aid in tissue repair.
- * In this study, sphingosine 1-phosphate (S1P) was found to significantly enhance cell survival and proliferation in kidney proximal tubule cells after I/R injury, demonstrating its potential in promoting tissue repair via specific signaling pathways, including the SAFE and JAK2/STAT3 pathways.
Effect of FADS1 SNPs rs174546, rs174547 and rs174550 on blood fatty acid profiles and plasma free oxylipins.
Front Nutr
July 2024
Medical Department B, Division of Hepatology, Gastroenterology, Oncology, Hematology, Palliative Care, Endocrinology and Diabetes, University Hospital Ruppin-Brandenburg, Brandenburg Medical School, Neuruppin, Germany.
Introduction: Previous studies have indicated that activity of fatty acid desaturase 1 (FADS1), is involved in cardiometabolic risk. Recent experimental data have shown that FADS1 knockdown can promote lipid accumulation and lipid droplet formation in liver cells. In this study, we aimed to characterize whether different FADS1 genotypes affect liver fat content, essential fatty acid content and free oxylipin mediators in the blood.
View Article and Find Full Text PDFPublic Awareness of Palliative Care: A Nationally Representative Sample of Jordanian Adults.
J Pain Symptom Manage
August 2024
Department of Adult Health Nursing (D.A.S.J.), Faculty of Nursing, The Hashemite University, Zarqa, Jordan.
Context: Internationally, studies suggest that inadequate comprehension of the concept of palliative care and misconceptions about it hinder the effective use of palliative care, especially in developing nations.
Objective: To assess the awareness of the adult population in Jordan regarding palliative care.
Methods: The study used a cross-sectional design and an online self-administered questionnaire survey.
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