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Triple pacing spikes on QRST: What is the mechanism?

J Electrocardiol

January 2025

Department of Cardiology, Electrophysiology division, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala 695011, India. Electronic address:

A septuagenarian man underwent dual chamber pacemaker (DDDR - Boston Scientific Massachusetts, U.S.) insertion for a complete heart block.

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Article Synopsis
  • - The study investigates the effectiveness of a new ECG technique called CineECG, which visualizes heart electrical activity, in improving cardiac resynchronization therapy (CRT) for patients who don't respond well to standard treatments.
  • - Researchers analyzed CineECG data from 15 patients with heart conditions under different pacing settings and found that specific movement directions in the heart's electrical signals correlate with better immediate heart performance (measured as dP/dt max).
  • - The results indicate that the direction of the ST-T segment during repolarization can predict a significant improvement in heart function during CRT, suggesting that CineECG could help optimize treatment plans for patients.
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Distal Ventricular Pacing for Drug-Refractory Mid-Cavity Obstructive Hypertrophic Cardiomyopathy: A Randomized, Placebo-Controlled Trial of Personalized Pacing.

Circ Arrhythm Electrophysiol

July 2024

Barts Heart Center, St Bartholomew's Hospital, Barts Health NHS Trust, London, United Kingdom (J.W.M., R.K.H., T.H., M.L., J.C.M., L.R.L., C.O.M., N.S., P.M.E., S.E.P., M.B.D., S.A.M.).

Background: Patients with refractory, symptomatic left ventricular (LV) mid-cavity obstructive (LVMCO) hypertrophic cardiomyopathy have few therapeutic options. Right ventricular pacing is associated with modest hemodynamic and symptomatic improvement, and LV pacing pilot data suggest therapeutic potential. We hypothesized that site-specific pacing would reduce LVMCO gradients and improve symptoms.

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Patients with Fontan physiology have reduced exercise performance compared to their peers as well as a higher incidence of bundle branch block (BBB). This study aims to investigate the association between BBB and exercise performance in the Fontan population through a retrospective review of the Pediatric Heart Network Fontan study public use dataset. "Low Performers" were defined as ≤ 25th percentile (for Fontan patients) for each exercise parameter at anaerobic threshold (AT) for gender and age and "Normal Performers" were all other patients.

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