AI Article Synopsis
- The main goal of osteoporosis treatment is to lower the risk of fractures.
- Bone-forming osteoporosis drugs are more effective than oral bisphosphonates as initial therapy, especially for patients at very high risk.
- After completing a course of these bone-building drugs, switching to anti-remodeling agents helps maintain and improve the benefits of treatment.
Article Abstract
Reducing fracture risk is the objective of osteoporosis treatment. Bone-forming osteoporosis drugs increase bone mass, restore bone microarchitecture, and reduce fracture risk more effectively than oral bisphosphonates, providing strong justification for the use of these agents as the initial therapy or after anti-remodeling agents in patients at very high risk of fracture. At the end of a 12-to-24-month course of osteoanabolic therapy, transitioning to a potent anti-remodeling agent maintains and enhances the treatment benefit. This review describes the clinical applications of osteoanabolic therapy for osteoporosis.
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| http://dx.doi.org/10.1080/00325481.2022.2069582 | DOI Listing |
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