Complex Flavanones from and Structural Revision of Oboflavanone A.

J Nat Prod

Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Chemical Biology Research Center, School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, People's Republic of China.

Published: June 2022

Nine new complex flavanones, cryptometcones A-I (-), along with four known analogues, were isolated from . The structures of - including their absolute configurations were elucidated by spectroscopic data analysis and electronic circular dichroism (ECD) calculations. In addition, the structure of oboflavanone A was revised, while the absolute configurations of oboflavanone B, cryptoflavanone C, and cryptoflavanone D were determined, according to their spectroscopic data. Compounds -, , and exhibited cytotoxicity against the HCT-116 cancer cell line.

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Source
http://dx.doi.org/10.1021/acs.jnatprod.2c00279DOI Listing

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