Mental illness (MI) stigma has been characterized as multi-dimensional including problems of knowledge (stereotypes), attitudes (prejudice) and behavior (discrimination); however, most research practice is predominantly applying unidimensional behavioral measures such as social distance scales. Moreover, specific types of MIs and different forms of discriminatory behaviors are not being differentiated. The Stereotype Content Model predicts that group stereotypes (warmth, competence) are linked with different forms of discriminatory behaviors (harm or facilitation) via emotional prejudices (pity, envy, contempt). The present study sought to establish how differential stereotypic perceptions of MI subgroups elicit distinct forms of behavioral discrimination via emotional prejudices. A community sample (N = 60) was randomly assigned to one of three conditions representing MIs across the warmth-competence stereotype space. Patterns of self-completed measures for stereotypes, emotions and behaviors differed significantly between conditions. The association between stereotypes and behaviors were largely mediated by emotions. Systematic patterns of stereotypic perceptions, emotional prejudices and behavioral discrimination are present for individuals with different types of MIs. Hence, generic measures of discrimination, such as social distance scales, may be misleading. Intervention strategies should consider the systematic variation of the factors involved in stigma, differentiating by type of MI and discriminatory behaviors.
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http://dx.doi.org/10.1111/sjop.12833 | DOI Listing |
Purpose: Vessels encapsulating tumor clusters (VETC) was implicated in the unfavourable prognosis of hepatocellular carcinoma (HCC). While potentially valuable for noninvasive evaluation, the proposed imaging criteria of VETC require external validation. This study aimed to evaluate the performance and prognostic value of these imaging criteria via CT and gadoxetic acid-enhanced MRI.
View Article and Find Full Text PDFEur J Cancer
January 2025
Department of Hematology, Oncology and Cancer Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany; German Cancer Consortium (DKTK), Berlin, Germany; Berlin Institute of Health (BIH), Berlin, Germany; Experimental and Clinical Research Center, A Cooperation of Charité-Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine, Berlin, Germany. Electronic address:
Background: Despite remarkable clinical efficacy, little is known about the system-wide immunological alterations provoked by PD1 blockade. Dynamics of quantitative immune composition and functional repertoire during PD1 blockade could delineate cohort-specific patterns of treatment response and therapy-induced toxicity.
Methods: We longitudinally assessed therapy-induced effects on the immune system in fresh whole blood using flow cytometry-based cell quantifications, accompanied by analyses of effector properties of all major immune populations upon cell-type specific stimulations.
Front Public Health
January 2025
School of Public Health, College of Health Sciences and Medicine, Dilla University, Dilla, Ethiopia.
Background: HIV continues to be a significant global health issue, particularly affecting sub-Saharan Africa, including Tanzania. Knowing one's HIV status is a crucial first step in combating HIV/AIDS and achieving the targets set for the Sustainable Development Goals (SDGs) by 2030. However, despite ongoing efforts, HIV testing coverage remains low in developing countries, including Tanzania, where testing among young people poses particular challenges.
View Article and Find Full Text PDFDigit Health
January 2025
School of IT and Engineering, Melbourne Institute of Technology, Melbourne, Australia.
Purpose: Breast cancer encompasses various subtypes with distinct prognoses, necessitating accurate stratification methods. Current techniques rely on quantifying gene expression in limited subsets. Given the complexity of breast tissues, effective detection and classification of breast cancer is crucial in medical imaging.
View Article and Find Full Text PDFQuant Imaging Med Surg
January 2025
Department of Medical Imaging, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China.
Background: The pattern of myocardial injury and dysfunction development during follow-up is unclear in patients with myocarditis. This study aims to explore the developmental pattern of myocardial injury and cardiac dysfunction during the follow-up of myocarditis by cardiac magnetic resonance (CMR) and differences in short-term follow-up CMR performance between patients with coronavirus disease 2019 (COVID-19)-associated myocarditis (CAM) and non-COVID-19-associated myocarditis (NCAM).
Methods: Data of patients with clinically diagnosed myocarditis who underwent follow-up CMR were retrospectively collected.
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