Background: Cleft lip and/or cleft palate (CLP) is a prevalent condition with a multifactorial etiology. An understanding of its etiologic factors discourages harmful habits and promotes societal acceptability.
Objectives: To assess the knowledge of environmental and genetic risk factors of CLP and determine its effect on predisposing social habits in a suburban community in Nigeria.
Methods: This was a descriptive cross-sectional study conducted at Ifo Local Government Area (LGA), Ogun state, Nigeria. Participants were adult residents of Ifo L.G.A. Knowledge of CLP categorized into description, environmental risk factors and genetic factors were assessed using a well structured interviewer administered questionnaire.
Results: A total of 300 adults (104 males; 196 females) aged 44.3 + 13.17 years with predominantly secondary level education participated in the study. Majority of participants (89.7%) had low overall knowledge of CLP including low knowledge on description of CLP (81.7%), environmental factors of CLP (81.3%), and genetic factors of CLP (93.7%). High level of education was significantly associated with increased knowledge on description of CLP (P < 0.05). No other significant association was noted between sociodemographic factors and knowledge of CLP. Decreased smoking history was associated with high knowledge on description of CLP (P = 0.043).
Conclusion: Majority of the population had low knowledge of CLP which was to an extent influenced by their lack of high level of education. This low knowledge was significantly associated with increased practices of social habits such as cigarette smoking that predispose unborn children to CLP. The low knowledge of CLP shown in this study highlights the need for increased community education and health promotion to encourage avoidance of risk factors that predispose to the condition and promote societal acceptability and quest for treatment of the condition.
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Codas
January 2025
Universidade Vale do Rio Doce - UNIVALE - Governador Valadares (MG), Brasil.
Purpose: To promote orientation about cleft lip and palate and to verify knowledge and satisfaction of an orientation program through a website developed for students and health professionals.
Methods: This is a cross-sectional study, 13 healthcare professionals and 81 students from the areas of nursing, speech-language pathologist, medicine, nutrition, dentistry, and psychology participated. The research consisted of three stages: filling out a pre-program questionnaire, accessing the website (http://fissuralabiopalatina.
Cleft Palate Craniofac J
January 2025
Centre for Appearance Research, University of West of England, Bristol, United Kingdom of Great Britain and Northern Ireland.
In 2012, the James Lind Alliance (JLA) worked with individuals with cleft lip and/or palate (CL/P), their families and clinicians to identify priority areas for future research. This article reviews progress conducted in the United Kingdom in the 3 JLA priorities most closely related to Clinical Psychology. It then builds upon the original priorities to identify 4 future directions, based on contemporary literature and in-depth discussions between clinical and research experts.
View Article and Find Full Text PDFJ Oral Biol Craniofac Res
January 2025
Researcher at the Egyptian Ministry of Health, PO Box 2111, Tanta, Egypt.
Cleft lip and palate (CLP) are a usually inherited anomaly described as a gap in the oral cavity's upper lip and/or roof. The etiology of CLP involves both genetic and environmental factors. The current study aimed to examine the genetic basis of nonsyndromic (NS) CLP (NSCL/P) and its association with specific genetic polymorphisms.
View Article and Find Full Text PDFFertil Steril
January 2025
Department of Health Behavior and Biological Sciences, School of Nursing, University of Michigan, Ann Arbor, Michigan.
Objective: To expand knowledge on physical outcomes and psychosocial experiences of oocyte donors after donation across 3 age cohorts.
Design: Cross-sectional mixed-methods survey.
Patients: A total of 363 participants (ages: 22-71 years, M = 38.
J Agric Food Chem
January 2025
Instituto de Hortofruticultura Subtropical y Mediterránea La Mayora, Universidad de Málaga-Consejo Superior de Investigaciones Científicas, Departamento de Microbiología, Universidad de Málaga, Málaga 29071, Spain.
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