Introduction: Vitamin D deficiency is a global health concern with over billions of people worldwide being vitamin D deficient or insufficient. Many epidemiological studies have reported cardiovascular diseases, autoimmune diseases and neoplastic diseases to be associated with vitamin D levels. This study aims to find out the prevalence of vitamin D deficiency in patients presenting to the outpatient Department of Medicine of a tertiary care center.
Methods: This was a descriptive cross-sectional study done among 362 patients in the outpatient Department of Medicine of a tertiary care center between May, 2016 and August, 2016. Ethical Approval was taken from Institutional Review Committee (Reference number: 21082015). Convenience sampling was done. Informed consent was obtained and data were collected. Data were analysed using the Statistical Package for the Social Science version 25.0. Point estimate at a 95% Confidence Interval was calculated along with frequency and percentages for binary data.
Results: Out of 362 patients, vitamin D deficiency was found in 215 (59.39%) (54.33-64.45 at 95% Confidence Interval) patients.
Conclusions: The prevalence of vitamin D deficiency was found to be lower to the other studies done in in similar settings. Physicians should be aware of the growing prevalence of vitamin D deficiency.
Keywords: avitaminosis; prevalence; vitamin deficiency.
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http://dx.doi.org/10.31729/jnma.7452 | DOI Listing |
Narra J
December 2024
Center for Preventive Medical Sciences, Chiba University, Chiba, Japan.
A worldwide issue, vitamin D deficiency affects pregnant mothers and babies everywhere, including Indonesia. It involves the adaptive immune system by controlling the production of pro-and anti-inflammatory cytokines and the balance between humoral (Th2) and cell-mediated (Th1) immunity. The aim of this study was to investigate the relationship between vitamin D and the cytokines IL-6 and IL-10 in infants.
View Article and Find Full Text PDFNarra J
December 2024
Department of Internal Medicine, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
The coexistence of depression and type 2 diabetes mellitus (T2DM) can significantly worsen disease prognosis and lower quality of life. Emerging evidence suggests that vitamin D deficiency contributes to the progression of T2DM and is closely associated with the development of depression. The aim of this study was to investigate the effects of cholecalciferol on depression in patients with T2DM, exploring its mechanisms by analyzing its impact on C-peptide, serotonin, and neurotrophin-3 levels.
View Article and Find Full Text PDFJ Bone Miner Metab
January 2025
The Affiliated Hospital of Guizhou Medical University, Guiyang, 550001, Guizhou, China.
Introduction: To investigate the relationship between serum high-density lipoprotein (HDL) cholesterol and bone mineral density (BMD) in vitamin D-deficient population.
Materials And Methods: This study was a cross-sectional study. From January to December 2020, 2583 middle-aged and older adult aged 40 and above were randomly selected in the Health Management Center of the Affiliated Hospital of Guizhou Medical University for health examination and questionnaire survey.
J Neurol
January 2025
Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Background: Neurologic symptoms seen in patients receiving immune checkpoint inhibitors (ICI) may not be entirely caused by immunotoxicity. We aim to highlight these confounding conditions through clinical cases to encourage early recognition and management.
Methods: We describe a series of seven cases from our institution that were treated with ICI and presented with Neurologic symptoms and were diagnosed with superimposed conditions beyond immunotoxicity.
GMS Ophthalmol Cases
December 2024
Department of Neuro-Ophthalmology, Aravind Eye Hospital and Postgraduate Institute, Coimbatore, India.
We present a case of a young woman who presented with blurring of vision in her right eye, worsening on near work. Detailed ophthalmic and neurological evaluation was done, which revealed light near dissociation, vermiform iris movements, constriction to diluted pilocarpine with absent deep tendon reflexes. Laboratory investigation indicated mild iron deficiency anemia and reduced vitamin D3 level.
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