HIV UTR, LTR, and Epigenetic Immunity.

Viruses

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.

Published: May 2022

The duel between humans and viruses is unending. In this review, we examine the HIV RNA in the form of un-translated terminal region (UTR), the viral DNA in the form of long terminal repeat (LTR), and the immunity of human DNA in a format of epigenetic regulation. We explore the ways in which the human immune responses to invading pathogenic viral nucleic acids can inhibit HIV infection, exemplified by a chromatin vaccine (cVaccine) to elicit the immunity of our genome-epigenetic immunity towards a cure.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146425PMC
http://dx.doi.org/10.3390/v14051084DOI Listing

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