Our objective is to evaluate the regional regenerative potential of calvarial bone in critical-sized defects in a rabbit model using novel nanostructured silica-loaded membranes doped with zinc or doxycycline. Nanostructured membranes of (MMA)-co-(HEMA)/(MA)-co-(HEA) loaded with 5 wt% of SiO nanoparticles (HOOC-Si-Membranes) were doped with zinc (Zn-HOOC-Si-Membrane) or doxycycline (Dox-HOOC-Si-Membrane). Critical bone defects were created on six New-Zealand-breed rabbit skulls and covered with the membranes. A sham defect without a membrane was used as the control. After six weeks, a histological analysis (toluidine blue technique) was employed to determine the area percentages of newly formed bone, osteoid bone, and soft tissue. The measurements were performed by dividing the total defect area into top (close to the membrane) and bottom (close to the dura mater) regions, or peripheral (adjacent to the old bone) and central (the sum of the remaining zones) regions. The peripheral regions of the defects showed higher osteogenic capacity than the central areas when the membranes were present. The proportion of new bone adjacent to the dura was similar to that adjacent to the membrane only when the HOOC-Si-Membranes and Zn-HOOC-Si-Membranes were used, indicating a direct osteoinductive effect of the membranes.
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http://dx.doi.org/10.3390/polym14102078 | DOI Listing |
ACS Appl Mater Interfaces
January 2025
Physical & Materials Chemistry Division, CSIR-National Chemical Laboratory, Pune, Maharashtra 411008, India.
This work aims to deal with the challenges associated with designing complementary bifunctional electrocatalysts and a separator/membrane that enables rechargeable zinc-air batteries (RZABs) with nearly solid-state operability. This solid-state RZAB was accomplished by integrating a bifunctional electrocatalyst based on Ru-RuO interface nanoparticles supported on nitrogen-doped (N-doped) graphene (Ru-RuO/NGr) and a dual-doped poly(acrylic acid) hydrogel (d-PAA) electrolyte soaked in KOH with sodium stannate additive. The catalyst shows enhanced activity and stability toward the two oxygen reactions, i.
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January 2025
School of Materials, Shenzhen Campus of Sun Yat-sen University, No. 66, Gongchang Road, Guangming District, Shenzhen, Guangdong 518107, P.R. China.
Indium (In) reduction is a hot topic in transparent conductive oxide (TCO) research. So far, most strategies have been focused on reducing the layer thickness of In-based TCO films and exploring TCOs. However, no promising industrial solution has been obtained yet.
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January 2025
Department of Physical Chemistry, Faculty of Chemistry, University of Tabriz, 29 Bahman Blvd., Tabriz, Iran.
Hydroxyapatite (HA) is an engineered biomaterial that closely resembles the hard tissue composition of humans. Biological HA is commonly non-stoichiometric and features lower crystallinity and higher solubility than stoichiometric HA. The chemical compositions of these biomaterials include calcium (Ca), phosphorus (P), and trace amounts of various ions such as magnesium (Mg), zinc (Zn), and strontium (Sr).
View Article and Find Full Text PDFInorg Chem
January 2025
Department of Material and Environmental Chemistry, Arrhenius Laboratory, Stockholm University, SE-10691 Stockholm, Sweden.
Zinc oxide (ZnO) is a semiconductor with a wide range of applications, and often the properties are modified by metal-ion doping. The distribution of dopant atoms within the ZnO crystal strongly affects the optical and magnetic properties, making it crucial to comprehend the structure down to the atomic level. Our study reveals the dopant structure and its contents in Eu-doped ZnO nanosponges with up to 20% Eu-O clusters.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Functional Materials and Electrochemistry Lab, Department of Chemistry, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal 721302, India.
The rational design and synthesis of bifunctionally active and durable oxygen electrocatalysts have garnered significant attention for electrochemical energy conversion and storage. Intermetallic nanostructures are particularly promising for these applications due to their unique catalytic properties and exceptional durability. In this study, we present a fascinating synthetic approach for the direct synthesis of a bifunctional oxygen electrocatalyst based on nitrogen-doped carbon-encapsulated ordered PdFe (o-PdFe@NC) intermetallic, using a cyano-bridged bimetallic single-source precursor tailored for aqueous rechargeable zinc-air batteries (ZABs).
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