Interest in the utilization of plant-based bioactive compounds in foods has increased due to their biochemical activities and as alternatives in the reduction of high concentrations of chemical utilization. However, some of these additives are hydrophobic, thus being harder to disperse into the hydrophilic food matrix. Therefore, an oil-in-water nanoemulsion (RRE1-RRE10) was formulated with different concentrations of red rice extract (1-10% /). Nanoemulsion showed droplet sizes within the range of 157.33-229.71 nm and the best formulation (RRE5) was selected based on the creaming index which was stable to flocculation over a range of temperatures (30-90 °C), pH (2-9), and salt concentration (100-600 mM). It showed significantly improved antioxidant and anti-inflammatory activity as compared to its other counterparts. Potential antimicrobial activity against was attributed to RRE5 nanoemulsion as compared to . Therefore, due to the potential bioactivity of RRE5 nanoemulsion, it can be scaled up at the industrial level.
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http://dx.doi.org/10.3390/polym14101938 | DOI Listing |
Drug Des Devel Ther
January 2025
Institute of Basic Theory for Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing, People's Republic of China.
Chin Med
December 2024
State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Background: Lovastatin, the main lipid-lowering component in red yeast rice, is a golden anti-lipid drug, but its long-term application is continuously challenged by potential skeletal muscle atrophy. Daidzein, an isoflavone derived from soybeans and many Chinese medicines, shows therapeutic potential in treating muscle-related diseases and metabolic disorders. However, whether daidzein can improve lovastatin-induced muscle atrophy and the specific mechanism needs to further study.
View Article and Find Full Text PDFJ Fungi (Basel)
November 2024
Department of Life Science, National Taitung University, Taitung 95092, Taiwan.
Monascinol (Msol), an analog of monascin (MS) produced by , possesses potential anti-inflammatory properties. This study compares the effects of SWM-008 fermented red mold rice, which contains the functional components MS and Msol, on liver and kidney damage related to diabetic complications in rats. An animal model of liver and kidney injury was induced by an intraperitoneal injection of streptozotocin (STZ) at 65 mg/kg body weight combined with nicotinamide (NA) at 150 mg/kg body weight.
View Article and Find Full Text PDFMethods Mol Biol
December 2024
Systems, Synthetic, and Physical Biology Program, Rice University, Houston, TX, USA.
Optogenetics enables precise control of gene expression in a variety of organisms. We recently developed the first system for optogenetic control of transcription in Bacillus subtilis. This system is based on CcaSR, a light-responsive two-component regulatory system originally derived from Synechocystis PCC 6803.
View Article and Find Full Text PDFHuan Jing Ke Xue
January 2025
State Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008, China.
In this investigation, the influence of organic amendment on the structural and functional dynamics of soil microbial communities and its effect on rice productivity were examined. Five fertilization treatments from a 40-year field experiment were selected: no fertilizer (CK), inorganic NPK fertilizer (NPK), inorganic NPK combined with green manure (NG), inorganic NPK combined with green manure and pig manure (NGM), and inorganic NPK combined with green manure and rice straw (NGS). The findings revealed that the organic amendment enhanced the soil organic carbon (SOC), total nitrogen (TN), and total phosphorus (TP) levels, alongside an increase in rice yield; notably, the most significant improvements were observed with the NGM treatment.
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