AI Article Synopsis
- Modern delivery techniques, like microneedles and hydrogels, enhance the permeability and effectiveness of natural bioactive products used for wound healing.
- Many natural products, such as curcumin and aloe vera, struggle to penetrate the skin barrier, limiting their therapeutic potential.
- This review highlights successful combinations of natural products and innovative delivery systems over the past two decades, aiming to create affordable and culturally accepted wound healing therapies.
Article Abstract
Application of modern delivery techniques to natural bioactive products improves their permeability, bioavailability, and therapeutic efficacy. Many natural products have desirable biological properties applicable to wound healing but are limited by their inability to cross the stratum corneum to access the wound. Over the past two decades, modern systems such as microneedles, lipid-based vesicles, hydrogels, composite dressings, and responsive formulations have been applied to natural products such as curcumin or aloe vera to improve their delivery and efficacy. This article reviews which natural products and techniques have been formulated together in the past two decades and the success of these applications for wound healing. Many cultures prefer natural-product-based traditional therapies which are often cheaper and more available than their synthetic counterparts. Improving natural products' effect can provide novel wound-healing therapies for those who trust traditional compounds over synthetic drugs to reduce medical inequalities.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143175 | PMC |
| http://dx.doi.org/10.3390/pharmaceutics14051072 | DOI Listing |
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