AI Article Synopsis
- The infrapatellar fat pad (IFP) is being studied for its role in knee osteoarthritis (OA), especially how it interacts with knee structures like cartilage and bone.
- The IFP releases pro-inflammatory substances that may contribute to the onset and progression of OA.
- The article will examine the advantages and risks of removing or preserving the IFP during total knee arthroplasties (TKAs) as there are currently no clear guidelines on the matter.
Article Abstract
In recent years, the infrapatellar fat pad (IFP) has gained increasing research interest. The contribution of the IFP to the development and progression of knee osteoarthritis (OA) through extensive interactions with the synovium, articular cartilage, and subchondral bone is being considered. As part of the initiation process of OA, IFP secretes abundant pro-inflammatory mediators among many other factors. Today, the IFP is (partially) resected in most total knee arthroplasties (TKA) allowing better visualization during surgical procedures. Currently, there is no clear guideline providing evidence in favor of or against IFP resection. With increasing numbers of TKAs, there is a focus on preventing adverse postoperative outcomes. Therefore, anatomic features, role in the development of knee OA, and consequences of resecting versus preserving the IFP during TKA are reviewed in the following article.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138316 | PMC |
| http://dx.doi.org/10.3390/biomedicines10051071 | DOI Listing |
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