Intrauterine growth restriction (IUGR) affects 5-10% of newborns and increases the risks of intrauterine demise, neonatal morbidity, and death. In their recent publication, Yeste et al. found the benefits of hydroxytyrosol supplementation on brain remodeling from an IUGR pig model. Additionally, we found a significant decrease in phenolic alcohol (tyrosol and hydroxytyrosol) intake in IUGR pregnant women. Altogether, these findings support the notion that dietetic interventions, through supplementation but mostly via a balanced diet, can ameliorate IUGR complications. Furthermore, diet intervention combined with early biomarkers may allow clinicians to eventually anticipate IUGR diagnosis and help avoid one of the most frequent causes of newborn mortality and morbidity.
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| http://dx.doi.org/10.3390/antiox11050833 | DOI Listing |
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Univ. Bordeaux, INSERM, Centre Bordeaux Population Health, Equipe Epicene, U1219, F-33000 Bordeaux, France; Univ Angers, CHU Angers, Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR S 1085, SFR ICAT, Poisoning Control Center - Prevention Federation, Angers, France; Epidemiology and Prevention, Donald and Barbare Zucket School of Medicine, Hofstra Univ Northwell Health, USA; CICEC.
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Xuzhou Clinical College of Xuzhou Medical University, Xuzhou Central Hospital, Xuzhou, China.
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