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| http://dx.doi.org/10.5489/cuaj.7948 | DOI Listing |
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Update on andrological effects of SARS-CoV-2 infection and COVID-19: An overview review.
Andrology
December 2024
Interdisciplinary Department of Medicine, School of Medicine, University of Bari "Aldo Moro", Bari, Italy.
Background: Evidence indicates a wide range of andrological alterations in patients with the Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) infection and Coronavirus Disease 2019 (COVID-19).
Aim: To provide an update on the andrological effects of SARS-CoV-2 infection and COVID-19.
Methods: PubMed/MEDLINE and Institutional websites were searched for randomized clinical trials, non-systematic reviews, systematic reviews, and meta-analyses.
The epigenetic approach of varicocele: a focus on sperm DNA and m6A-RNA methylation.
Hum Reprod Update
December 2024
Department of Animal Biotechnology, Reproductive Biomedicine Research Center, Royan Institute for Biotechnology, ACECR, Isfahan, Iran.
Background: Varicocele is an abnormal dilation and torsion of the pampiniform venous plexus in the scrotum due to venous reflux, primarily affecting the left side. It affects 15% of men and is a prevalent contributor to male infertility. Varicocele is a complex disorder influenced by genetic, epigenetic, and environmental factors.
View Article and Find Full Text PDFThe ductal network in the human testis and epididymis: What belongs to which?
Clin Anat
November 2024
Klinik für Urologie, Universitätsklinikum Schleswig-Holstein, Lübeck, Germany.
Article Synopsis
- The testes and epididymis have a network of tubules responsible for sperm generation, maturation, nourishment, and transport, including the efferent ductules connecting the rete testis to the epididymis.
- There is a debate over whether the efferent ductules belong to the testicles or the epididymis, but clinical evidence supports their classification with the epididymis.
- Correctly identifying components of the epididymis is crucial for assessing testicular cancers, as infiltration by tumors can affect prognosis.
Testicular immunity.
Mol Aspects Med
December 2024
Reproductive Sciences Center, Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45267, USA. Electronic address:
Article Synopsis
- * Key factors supporting testicular immune privilege include the blood-testis barrier, specialized immune cells, Sertoli cells' immunomodulation, and high steroid hormone levels.
- * Disruption of testicular immunity by infections or autoimmune reactions can lead to infertility and damage to germ cells, highlighting the need for further research to understand and improve treatments related to male fertility.
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