Emulsion as a fine dispersion of immiscible liquids has involved widespread applications in industry, pharmaceuticals, agriculture, and personal care. Stimuli-responsive emulsions capable of on-demand demulsification or changing their properties are required in many cases such as controllable release cargo, oil recovery, emulsifier recycling, and product separation, great progress is achieved in these areas. Among these various triggers, much effort is made to develop physical stimuli, due to the noninvasive and environmentally friendly characteristics. Physical stimuli-responsive emulsions provide plenty of valuable practical applications in the fields of sustainable industry, biomedical reaction, drug delivery. Here, the recent development in the field of emulsions in response to physical stimuli consisting of temperature, light, magnetic fields, electrical fields, etc., is summarized. The preparation methods and mechanisms of physical stimuli-responsive emulsions and their applications of catalysis reaction, drug delivery, and oil recovery are highlighted in this review. The future directions and outstanding problems of the physical stimuli-responsive emulsions are also discussed.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/marc.202200193 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Supramolecular assembly strategy of modified starch chains for achieving recyclable emulsion biocatalysis within a narrow pH range.
Carbohydr Polym
January 2025
State Key Laboratory of Materials-Oriented Chemical Engineering, School of Pharmaceutical Sciences, Nanjing Tech university, Nanjing 210009, Jiangsu Province, PR China.
Stimuli-responsive Pickering emulsions are promising in biocatalysis for their ease of product separation and emulsifier recovery. However, pH responsiveness, though simple and cost-effective, faces challenges in precise control and narrow transition ranges, limiting its use in enzymatic catalysis. Herein we introduced amorphous octenyl succinic anhydride-modified debranched starch chains (Am-OSA-St) to control emulsion properties within a pH range suitable for enzymatic catalysis.
View Article and Find Full Text PDFDose-effect relationship of copolymer on enhancing aqueous lubrication of a hybrid osteoarthritis drug delivery nanocarrier.
J Colloid Interface Sci
February 2025
State Key Laboratory of Solidification Processing, Center of Advanced Lubrication and Seal Materials, School of Materials Science and Engineering, Northwestern Polytechnical University, Xi'an 710072, PR China. Electronic address:
Developing stimulus-responsive properties of drug delivery nanocarriers combined with enhanced joint lubrication is an effective synergistic strategy for treating osteoarthritis. Poly(N-isopropylacrylamide) (PNIPAm) is a typical thermo-responsive polymer, which can achieve drug delivery by transition from swollen state to collapsed state. However, undesired transition temperature, limited drug loading capacity, and weakened mechanical properties in joint present obstacles to use as drug delivery nanocarriers.
View Article and Find Full Text PDFEnabling oral novel Taxanes-based Chemotherapy with Lipophilic prodrug Self-nanoemulsifying drug delivery system.
Bioorg Chem
December 2024
Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China; Joint International Research Laboratory of Intelligent Drug Delivery Systems, Ministry of Education, Shenyang 110016, China. Electronic address:
Larotaxel (LTX) and SB-T-1214 (SBT), two new synthetic experimental toxoids, have shown broad-spectrum antitumor activity, especially against tumors that are resistant to other drugs. However, their poor solubility, membrane permeability, and first-pass effect limits their use in oral administration. We designed and synthesized two long-chain triglyceride-mimic prodrugs of LTX (LTXSSTG) and SBT (SBTSSTG), which are bridged by disulfide bonds and efficiently incorporated them into Self-nanoemulsifying drug delivery system (SNEDDS).
View Article and Find Full Text PDFPickering emulsions for stimuli-responsive transdermal drug delivery: effect of rheology and microstructure on performance.
Soft Matter
November 2024
Department of Chemical Engineering, University College London, London, UK.
This work investigates the design of stimuli-responsive Pickering emulsions (PEs) for transdermal drug delivery applications, by exploring the impact of stabilising microgels size and interactions on their rheological and release properties. Temperature-responsive poly(-isopropylacrylamide) microgels modified with 1-benzyl-3-vinylimidazolium bromide (pNIPAM--BVI) are synthesized in varying sizes and used to stabilise jojoba oil-in-water concentrated emulsions. The results reveals two distinct behaviours: for small microgels (∼300 nm), the PEs exhibit a smooth, uniform structure characterised by a mild yield stress, characteristic of soft glassy systems.
View Article and Find Full Text PDFDesign of stimuli-responsive minimalist heptad surfactants for stable emulsions.
Commun Mater
October 2024
School of Chemical Engineering, Faculty of Science, Engineering and Technology, The University of Adelaide, Adelaide, SA 5005 Australia.
Peptide surfactants have been extensively investigated with various applications in detergents, foods, and pharmaceutics due to their biodegradability, biocompatibility, and customizable structures. Traditional peptide surfactants are often designed in a head-to-tail fashion mimicking chemical surfactants. Alternatively, a side-by-side design pattern based on heptad repeats offers an approach to designing peptide surfactants.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!