Africa is one of the regions with high mycotoxin contamination of foods and continues to record high incidences of liver cancers globally. The agricultural sector of most African countries depends largely on climate variables for crop production. Production of mycotoxins is climate-sensitive. Most stakeholders in the food production chain in Africa are not aware of the health and economic effects of consuming contaminated foods. The aim of this review is to evaluate the main factors and their degree of contribution to the high levels of mycotoxins in African foods. Thus, knowledge of the contributions of different factors responsible for high levels of these toxins will be a good starting point for the effective mitigation of mycotoxins in Africa. Google Scholar was used to conduct a systemic search. Six factors were found to be linked to high levels of mycotoxins in African foods, in varying degrees. Climate change remains the main driving factor in the production of mycotoxins. The other factors are partly man-made and can be manipulated to become a more profitable or less climate-sensitive response. Awareness of the existence of these mycotoxins and their economic as well as health consequences remains paramount. The degree of management of these factors regarding mycotoxins varies from one region of the world to another.
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http://dx.doi.org/10.3390/toxins14050318 | DOI Listing |
Behav Brain Sci
January 2025
Department of Human Development and Quantitative Methodology, University of Maryland, College Park, College Park, MD,
In their article, Murayama and Jach contend that a mental computational model demonstrates that high-level motivations are emergent properties from underlying cognitive processes rather than instigators of behaviors. Despite points of agreement with the authors' critiques of the motivation literature, I argue that their claim of dismantling the black box of the human mind has been constructed on shaking grounds.
View Article and Find Full Text PDFJ Exp Biol
January 2025
Dept of Biological Sciences, University of Arkansas, Fayetteville AR 72701, USA.
Altered food landscapes contribute importantly to wildlife disease dynamics and may play an important role in host heterogeneity in disease outcomes through changes in host diet composition. We explored the effects of dietary macronutrient composition on disease pathology and feeding behavior of canaries (Serinus canaria domestica) infected with Mycoplasma gallisepticum (MG). In the first experiment, we provided canaries with isocaloric diets comprised of identical ingredients that varied in macronutrient content (high-protein or high-lipid) then MG- or sham-inoculated birds.
View Article and Find Full Text PDFS Afr J Surg
December 2024
Division of Surgery, Tygerberg Hospital, Stellenbosch University, South Africa.
Background: Bowel trauma, encompassing injuries to the small and large intestine, represents a significant medical challenge due to its potential for morbidity and mortality. Management of bowel injuries remains surgical, but multiple factors influence the outcome in these patients. This study provides an in-depth analysis of the high-risk features of hollow visceral trauma in the ICU setting and the corresponding mortality rates, shedding light on the critical factors that influence outcomes in these cases.
View Article and Find Full Text PDFComput Methods Biomech Biomed Engin
January 2025
Department of Electronics and Electrical Communications, Faculty of Electronic Engineering, Menoufia University, Menouf, Egypt.
The conversion of a person's intentions into device commands through the use of brain-computer interface (BCI) is a feasible communication method for individuals with nervous system disorders. While common spatial pattern (CSP) is commonly used for feature extraction in BCIs, it has limitations. It is known for its susceptibility to noise and tendency to overfit.
View Article and Find Full Text PDFComb Chem High Throughput Screen
January 2025
Hebei Key Laboratory of Specialty Animal Germplasm Resources Exploration and Innovation, College of Animal Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao, China.
Background: Methotrexate (MTX) effectively eliminates cancerous cells but can also cause inflammation intestinal, known as mucositis. Forsythiaside A (FTA) from Forsythia suspensa has shown promise in relieving mucositis by targeting the NLRP3 pathways. Since NLRP3 inflammasome activation is negatively regulated by autophagy, this study explores how FTAmediated autophagy affects NLRP3 inflammasome in treating MTX-induced intestinal inflammation.
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