Background: Laryngopharyngeal reflux (LPR) may be associated with the severity of obstructive sleep apnea (OSA). However, it is unknown whether LPR may be associated with arousal.
Objective: To clarify the effect of LPR on arousal in OSA.
Methods: This study included 120 OSA patients. The correlations between LPR scores and arousal index (ArI) were analyzed. Finally, to further clarify the effect of LPR on ArI, we analyzed the correlations between respiratory event-related arousal index (BERAI), leg-movement-related arousal index (LMRAI), snore-related arousal index (SRAI), spontaneous arousal index (SAI), and RSI score.
Results: Partial correlation analysis showed that the RSI score was positively correlated with ArI ( = .000), mainly correlated with BERAI and SAI ( = 0.422, = .000; = 0.212, = .020). While controlling for apnea-hypopnea index (AHI), the RSI score was still positively correlated with ArI ( = .002), mainly correlated with BERAI and SAI ( = 0.252, = .006; = 0.200, = .029).
Conclusions And Significance: The effect of LPR symptoms on arousal in OSA exists. The more severe the LPR was, the more frequent the arousal in OSA patients was. Thereinto, respiratory event-related arousal and spontaneous arousal were the most obvious.
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http://dx.doi.org/10.1080/00016489.2022.2075033 | DOI Listing |
Sci Rep
December 2024
Psychology Department, University of Illinois at Urbana Champaign, Champaign, United States.
Efficient searches are guided by target-distractor distinctiveness: the greater the distinctiveness, the faster the search. Previous research showed that when the target and distractors differ along both color and shape dimensions (i.e.
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December 2024
Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, China.
Amblyopia affects more than visual acuity. To compare the performances of visual selective attention and numerical processing in children with anisometropic amblyopia and children with normal vision, and investigate whether performance would be improved after visual acuity recovery, we performed 3 visual attention tasks (identifying number location task, numerical comparison task, and specific number comparison task) in children with anisometropic amblyopia, children who had recovered from anisometropic amblyopia, and children with normal vision in 6-8 and 9-11 years groups. The numerical processing ability, visual selective attention, and numerical distance effect were assessed by their reaction time of different tasks.
View Article and Find Full Text PDFCommun Biol
December 2024
Department of Physiology, School of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, Anhui, China.
Dexmedetomidine (DexM), a highly selective α-adrenoceptor agonist, significantly reduces postoperative adverse effects, including sleep and circadian rhythm disruptions. Vasoactive intestinal peptide neurons in the suprachiasmatic nucleus (SCN) regulate the synchronization of circadian rhythms with the external environment in mammals. We investigate the effects of DexM on sleep and circadian rhythms, as well as the underlying mechanisms.
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December 2024
Department of Preventive Intervention for Psychiatric Disorders, National Institute of Mental Health, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi-cho, Kodaira, Tokyo, 187-8553, Japan.
Pupil dilation is considered to track the arousal state linked to a wide range of cognitive processes. A recent article suggested the potential to unify findings in pupillometry studies based on an information theory framework and Bayesian methods. However, Bayesian methods become computationally intractable in many realistic situations.
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December 2024
Department of Neurosurgery, Baylor College of Medicine, Houston, USA.
Alteration of responses to salient stimuli occurs in a wide range of brain disorders and may be rooted in pathophysiological brain state dynamics. Specifically, tonic and phasic modes of activity in the reticular activating system (RAS) influence, and are influenced by, salient stimuli, respectively. The RAS influences the spectral characteristics of activity in the neocortex, shifting the balance between low- and high-frequency fluctuations.
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