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Clinical Impact of Heart Team Decisions for Patients With Complex Valvular Heart Disease: A Large, Single-Center Experience. | LitMetric

AI Article Synopsis

  • A multidisciplinary "heart team" approach for managing patients with valvular heart disease (VHD) was implemented at a hospital since 2014, gathering data on patient characteristics, treatment recommendations, and outcomes.
  • In a study of 1004 hospitalized VHD patients with high clinical complexity, 80% received interventional treatments, while 20% were managed conservatively, with only 5% changing treatment plans.
  • The early mortality rate was low at 2.4%, with significantly better outcomes than expected predictions based on surgical risk scores, indicating that this collaborative management strategy is both feasible and effective.

Article Abstract

Background A multidisciplinary approach might be pivotal for the management of patients with valvular heart disease (VHD), but clinical outcome data are lacking. Methods and Results At our institution, since 2014, internal guidelines recommended heart team consultations for patients with VHD. The clinical/echocardiographic characteristics, treatment recommendations, performed treatment, and early clinical outcomes of consecutive, hospitalized patients with VHD undergoing heart team evaluation were collected. Surgical risk was prospectively assessed by the EuroSCORE II and STS-PROM. The primary end point of the study was early mortality. A total of 1004 patients with VHD with high clinical complexity (mean age, 75 years; mean EuroSCORE II, 9.4%; mean STS-PROM, 5.6%; 48% ischemic heart disease; 29% chronic kidney disease, 9% oncologic/hematologic diseases) were enrolled. The heart team recommended an interventional treatment for 807 (80%) patients and conservative management for 197 (20%) patients. Management crossovers occurred in only 5% of patients. The recommended intervention was cardiac surgery for 230 (23%) patients, percutaneous treatment in 516 (51%) patients, and hybrid treatment in 61 (6%) patients. Early mortality occurred in 24 patients (2.4%) and was independently predicted by aortic stenosis, left ventricular ejection fraction, pulmonary artery systolic pressure, and conservative management recommendation. In patients referred to treatment, observed early mortality (1.7%) was significantly lower (<0.001) than expected on the bases of both the STS-PROM (5.2%) and EuroSCORE II (9.7%). Conclusions Within the limitations of its single-center and observational design, the present study suggests that heart team-based management of patients with complex VHD is feasible and allows referral to a wide spectrum of interventions with promising early clinical results.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238748PMC
http://dx.doi.org/10.1161/JAHA.121.024404DOI Listing

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