Background: Despite its well-known effectiveness in vertebral compression fractures (VCFs), kyphoplasty could also bring the risk of developing subsequent VCFs post-augmentation, especially at adjacent vertebrae, which has been rarely reported in Asian countries.
Methods: In this cross-sectional study, we performed cement augmentation on 69 vertebrae in 65 patients at the Spine Surgery Department, Viet Duc University Hospital, from June 2019 to November 2020. Cement augmentation was performed on 69 vertebrae in 65 patients. They then were followed and assessed for subsequent VCFs every 3, 6, 9 months after surgery.
Results: 69 vertebrae in 65 patients were treated by kyphoplasty, 2 patients had 2 vertebrae treated and only one patient had 3 vertebrae injected. The average age recorded was 72 ± 8 years old. The average amount of cement injected was 5.4 ± 1.4 ml per vertebrae. At the end of the study, 63 patients did not develop subsequent VCFs. Two patients (3.07%) had new VCFs post-augmentation within the first two-month period post-injection. Age, gender, history of steroid injection and number of vertebrae treated with kyphoplasty showed no significant difference between the two groups.
Conclusions: Kyphoplasty is an effective pain-reliving treatment for patients with osteoporotic VCFs and would pose no threats to subsequent VCFs. For patients developing abnormal acute pain within the period of two months, further examinations and MRI scan should be performed to detect subsequent VCFs in time.
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http://dx.doi.org/10.1016/j.amsu.2022.103756 | DOI Listing |
Clin Spine Surg
October 2024
Department of Orthopedic Surgery, National Taiwan University Hospital, Taipei, Taiwan.
Study Design: A retrospective cohort study.
Objective: The study retrospectively analyzed the factors associated with the development of adjacent vertebral fractures.
Summary Of Background Data: Adjacent vertebral fractures (AVF) may occur following cement vertebroplasty, and several risk factors have been reported with controversies.
J Appl Physiol (1985)
December 2024
Department of Physiology, Lovelace Biomedical Research Institute, Albuquerque, New Mexico, United States.
Intravenous bolus (IVb) injection of fentanyl induces an immediate apnea, but the characteristics of the apnea and relevant mechanism remain unclear. Here, we tested whether IVb injection of fentanyl induced an immediate central and upper airway obstructive apnea associated with chest wall rigidity via activating vagal C-fibers (VCFs) and vagal afferent opioid receptors (ORs). Cardiorespiratory and electromyography of external and internal intercostal, thyroarytenoid, and superior pharyngeal constrictor muscles (EMG, EMG, EMG and EMG) responses to IVb injection of fentanyl were recorded in anesthetized and spontaneously breathing rats with or without bilateral perivagal capsaicin treatment or intravagal microinjection of naloxone.
View Article and Find Full Text PDFPlast Reconstr Surg
October 2024
Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Gyeonggi-do, South Korea.
Background: Early detection of rare genetic diseases, including velocardiofacial syndrome (VCFS), is essential for patient well-being. However, their rarity and limited clinical experience of physicians make diagnosis challenging. Deep learning algorithms have emerged as promising tools for efficient and accurate diagnosis.
View Article and Find Full Text PDFCureus
August 2024
Department of Neurosurgery, Taipei Veterans General Hospital, Taipei, TWN.
While osteoporosis is the primary cause of vertebral compression fractures (VCFs), it's crucial to promptly recognize pathological fractures through comprehensive diagnostic tests, including vertebral biopsies, to determine the exact etiology. For instance, a 66-year-old male with osteoporosis experienced worsening lower limb weakness and back pain after an initial vertebroplasty for a T12 compression fracture. Subsequent MRI revealed severe circumferential extradural compression at T12, leading to further surgeries that eventually uncovered metastatic adenocarcinoma from a pancreatic tumor.
View Article and Find Full Text PDFJ Clin Med
August 2024
Department of Orthopaedic Surgery, Keck School of Medicine, The University of Southern California, Los Angeles, CA 90033, USA.
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