A 13-year-old white male was found to have a melanoma of the iris. Three treatments with xenon arc photocoagulation resulted in regression of the lesion with development of an iris coloboma. There were no complications, and corrected visual acuity has remained at 20/15 after a 19-year follow-up.
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Endocrine
January 2025
Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
The word "cancer" evokes myriad emotions, ranging from fear and despair to hope and determination. Cancer is aptly defined as a complex and multifaceted group of diseases that has unapologetically led to the loss of countless lives and affected innumerable families across the globe. The battle with cancer is not only a physical battle, but also an emotional, as well as a psychological skirmish for patients and for their loved ones.
View Article and Find Full Text PDFPan Afr Med J
January 2025
Department of Ophthalmology, Faculty of Medicine Universitas Airlangga, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Anterior segment dysgenesis exerts its influence on a diverse array of ocular structures, encompassing the cornea, iris, ciliary body, anterior chamber and lens. We present a 20-month-old boy with bilateral corneal opacity. The visual acuity (VA) was 6/480 in both eyes.
View Article and Find Full Text PDFJ Environ Manage
January 2025
Heilongjiang Province Key Laboratory of Geographical Environment Monitoring and Spatial Information Service in Cold Regions, School of Geographical Sciences, Harbin Normal University, Harbin, 150025, China; Heilongjiang Province Collaborative Innovation Center of Cold Region Ecological Safety, Harbin, 150025, China. Electronic address:
Nitrogen and phosphorus inputs to surface water bodies lead to a decline in water quality and a disruption in the balance of aquatic ecosystems. Emergent aquatic plants were widely used for their high efficiency in removing nitrogen and phosphorus from surface waters. However, there was a lack of systematic analyses on the purification of surface waters by emergent aquatic plants, and the mechanism of differences in nitrogen and phosphorus removal by different plants needs to be further revealed.
View Article and Find Full Text PDFAge Ageing
January 2025
Aging Research Center, Department Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
Objective: We aimed to investigate the association of sociodemographic, clinical and functional characteristics with the volume of transitions and specific trajectories across living and care settings.
Methods: Using data from the Swedish National Study on Aging and Care in Kungsholmen study, we identified transitions across home (with or without social care), nursing homes, hospitals and postacute care facilities among 3021 adults aged 60+. Poisson and multistate models were used to investigate the association between sociodemographic, clinical and functional characteristics and both the overall volume and hazard ratios (HRs) of specific transitions.
Viruses
January 2025
College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA 91766, USA.
Background: HIV and tuberculosis (TB) co-infection poses a significant health challenge, particularly when involving the central nervous system (CNS), where it leads to severe morbidity and mortality. Current treatments face challenges such as drug resistance, immune reconstitution inflammatory syndrome (IRIS), and persistent inflammation. Glutathione (GSH) has the therapeutic potential to enhance treatment outcomes by improving antibiotic efficacy, reducing inflammation, and mitigating immune dysfunction.
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