Objective: The coexisting overactive-underactive bladder (COUB) syndrome could be related to the increased urethral resistance caused by severe pelvic organ prolapse (POP). We aimed to evaluate the clinical and urodynamic findings of patients with COUB and/or detrusor overactivity-underactivity (DOU) in a cohort of patients scheduled for POP surgery and the possible risk factors of COUB after surgery.
Methods: This retrospective study analyzed all patients who underwent POP repair between 2008 and 2013, excluding women with a history of pelvic floor surgery. Patients were divided into COUB and non-COUB according to baseline symptoms and into DOU and non-DOU based on urodynamic findings. A multivariate model was performed to identify risk factors for COUB symptoms after surgery.
Results: A total of 533 women underwent POP surgery. Preoperatively, patients with COUB had more severe anterior compartment prolapse (Pelvic Organ Prolapse Quantification staging system Aa point, P = 0.008) and more frequently had overactive bladder compared with controls (P = 0.023). The rate of COUB decreased significantly after surgery. Preoperative opening detrusor pressure resulted as the only independent predictor of postoperative COUB symptoms (P = 0.034).
Conclusion: POP is a valid pathogenetic model for COUB development. POP repair induced a significant decrease in COUB symptoms with low opening detrusor pressure resulting as the only independent predictor of postoperative COUB.
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http://dx.doi.org/10.1002/ijgo.14288 | DOI Listing |
J Family Med Prim Care
December 2024
Department of Obstetrics and Gynecology, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
Gastrointestinal stromal tumors (GISTs) are rare mesenchymal tumors that arise from interstitial cells of Cajal. Due to vague presentation, location and confusing imaging studies, they tend to mimic gynaecological tumors. They usually diagnosed intra-operative and histopathology followed by tumor specific receptors such as KIT, CD34, CD 117 and DOG 1 are mainstay of diagnosis of GIST.
View Article and Find Full Text PDFHCA Healthc J Med
December 2024
Menorah Medical Center, Overland Park, KS.
Background: Testicular seminoma is the most common malignant tumor of the testis. It occurs at a rate of 5 per 100 000 men, primarily between the ages of 15 to 34. While seminomas typically occur in the testis, other primary sites include the mediastinum, the retroperitoneum, or other extra-gonadal sites.
View Article and Find Full Text PDFEur J Obstet Gynecol Reprod Biol
December 2024
Department of Obstetrics and Gynaecology, Caen University Hospital, Caen, France; Inserm U1086 "ANTICIPE", Unité de Recherche Interdisciplinaire pour la Prévention et le Traitement des Cancers, Caen, France.
Introduction: Vaginal pessaries are offered as a first-line treatment for symptoms associated with pelvic organ prolapse (POP). The objective of our study was to identify risk factors for failure of pessary use within 1 year of insertion.
Materials And Methods: We prospectively included women who accepted a pessary fitting for symptomatic POP.
Eur J Obstet Gynecol Reprod Biol
December 2024
Ruth and Bruce Rappaport, Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel; Department of Obstetrics and Gynecology, Carmel Medical Center, Haifa, Israel.
Introduction: The rising prevalence of pelvic organ prolapse (POP) in the aging population underscores the need to reevaluate treatment options. This study examines obliterative procedures, specifically colpocleisis performed with (CH) and without (C) concomitant vaginal hysterectomy, as management strategies for frail, non-sexually active elderly patients with advanced prolapse.
Methods: This retrospective study analyzed data from patients who underwent either colpocleisis with concomitant vaginal hysterectomy (CH) or colpocleisis alone (C) at our institution between 2006 and 2020.
Int J Surg Case Rep
December 2024
Department of Obstetrics and Gynecology, Mahatma Gandhi Institute of Medical Sciences, Wardha, India. Electronic address:
Introduction And Importance: Xanthogranulomatous inflammation of the female genital tract is a rare condition involving ovarian tubes characterized by chronic inflammation and destruction of pelvic organs, often mimicking pelvic malignancy.
Case Presentation: A 37-year-old female with a history of chronic kidney disease, hypertension, and treated pulmonary tuberculosis, presented with lower abdominal fullness, pain, and irregular menstrual cycles.
Clinical Discussion: Radiological investigations revealed a significant left adnexal mass, suggesting a tubo-ovarian abscess or neoplastic lesion.
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