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http://dx.doi.org/10.1007/s11356-022-21055-7 | DOI Listing |
Microb Pathog
December 2024
Department of Biology, Faculty of Science, Arak University, Arak, 38156-8-8349, Iran.
Cureus
November 2024
Physical Medicine and Rehabilitation, St. John's National Academy of Health Sciences, Bengaluru, IND.
Emery-Dreifuss Muscular Dystrophy (EDMD) is a rare genetic disorder characterized by muscle weakness, joint contractures, and cardiac dysfunction. Within this spectrum, EDMD Type 2, attributed to a heterozygous missense variant in exon 9 of the LMNA gene, presents a distinctive clinical profile. This case report details the presentation and management of a teenage girl displaying neck, trunk, upper and lower limb weakness, Achilles tendon contracture, and lordosis.
View Article and Find Full Text PDFFront Genet
December 2024
Department of Biophysics, Laboratory of DNA Repair and Aging, Institute of Biosciences, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
To understand the transcriptomic profile of an individual cell in a multicellular organism, we must comprehend its surrounding environment and the cellular space where distinct molecular stimuli responses are located. Contradicting the initial perception that RNAs were nonfunctional and that only a few could act in chromatin remodeling, over the last few decades, research has revealed that they are multifaceted, versatile regulators of most cellular processes. Among the various RNAs, long non-coding RNAs (LncRNAs) regulate multiple biological processes and can even impact cell fate.
View Article and Find Full Text PDFDiagnostics (Basel)
November 2024
Faculty of Medicine, Primary Care Physician, Recep Tayyip Erdogan University, Rize 53100, Türkiye.
Background And Objective: Diabetes Mellitus is a long-term, multifaceted metabolic condition that necessitates ongoing medical management. Hypogonadism is a syndrome that is a clinical and/or biochemical indicator of testosterone deficiency. Cross-sectional studies have reported that 20-80.
View Article and Find Full Text PDFJ Prosthodont
December 2024
Private practice, Inspired Orthodontics, Seattle, Washington, USA.
The "gummy smile" is a complex developmental issue that requires a three-dimensional approach to diagnosis and treatment. This article explores the multifaceted nature of the gummy smile, tracing its origins to early childhood growth patterns and breathing dysfunctions. It emphasizes the importance of understanding the interplay between skeletal development, soft tissue function, and breathing modalities in the formation of craniofacial structures.
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