Two new sesquiterpenoids, flammupin A () and flammupin B (), along with two known compounds, enokipodin C () and 5,5'-dibuthoxy-2,2'-bifuran () were obtained from , an endophytic fungus isolated from the roots of Maxim. The structures were elucidated by the combination of HR-ESI-MS, NMR, and ECD analyses. Compound exhibited moderate to potent cytotoxicity against A549, HeLa, and SMMC-7721 cells with IC values ranged from 3.69 to 11.84 μM.
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http://dx.doi.org/10.1080/10286020.2022.2077199 | DOI Listing |
Chem Biodivers
December 2024
Southern Medical University, School of Pharmaceutical Sciences, 1838 Guangzhou Avenue North, 510515, Guangzhou, CHINA.
Twelve new compounds, named fuscoposides A -L (1-12), including two phenolic, nine benzenoid, and one phenylethanoid glucosides, were isolated from the mangrove endophytic fungus Fuscoporia sp. A2A6. The structures of these compounds were established by HRESIMS, NMR spectroscopic data, single-crystal X-ray diffraction analysis, and chemical methods.
View Article and Find Full Text PDFMol Ecol Resour
December 2024
Department of Botany, University of British Columbia, Vancouver, British Columbia, Canada.
Relatively little is known of the host associations and compatibility of fungal plant pathogens and endophytes. Publicly available plant genomic DNA can be mined to detect incidental fungal DNA, but taxonomic assignment can be challenging due to short lengths and variable discriminative power among different genomic regions and taxa. Here, we introduce a computationally lightweight and accessible Snakemake pipeline for rapid detection and classification (identification and assignment to taxonomic rank) of pathogenic and endophytic fungi (and other fungi associated with plants) that targets the internal transcribed spacer (ITS) region, a fungal barcode standard.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Plant Pathology, Faculty of Agriculture, Annamalai University, Chidambaram, India.
Endophytes isolated from seaweeds emerge as promising biocontrol agents against broad spectrum of plant diseases. The endophytic bacteria were isolated from the seaweed (Sargassum wightii) to manage the chilli fruit rot pathogen Fusarium incarnatum. The antifungal activity of the isolated bacteria was tested by dual culture assay and plant growth-promoting activity was also tested by the standard paper towel method.
View Article and Find Full Text PDFISME Commun
January 2024
School of Environmental and Forest Sciences, College of the Environment, University of Washington, Seattle, WA 98195-2100, United States.
Endophytes are microbes living within plant tissue, with some having the capacity to fix atmospheric nitrogen in both a free-living state and within their plant host. They are part of a diverse microbial community whose interactions sometimes result in a more productive symbiosis with the host plant. Here, we report the co-isolation of diazotrophic endophytes with synergistic partners sourced from two separate nutrient-limited sites.
View Article and Find Full Text PDFCureus
November 2024
Department of Oral Pathology and Microbiology, Manav Rachna Dental College, Faridabad, IND.
Introduction Oral verrucous carcinoma (OVC), a low-grade variation of oral squamous cell carcinoma (OSCC), is distinguished by endophytic development and a pebbly, mammillated surface. OVC, often referred to as Ackerman's tumor, has been known to involve lymph nodes but rarely spreads to regional and distant locations; when the primary tumor grows, it frequently involves surrounding tissues. Histopathologically, it has a thicker basement membrane, many reduplications, and a large area of inflammatory infiltration that resembles OSCC.
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