AI Article Synopsis
- Gastrointestinal dysfunction is common in patients with neuromuscular diseases but is often overlooked, leading to serious health issues.
- A case-series involving six patients with different neuromuscular disorders highlights the challenges associated with gastrointestinal problems such as dysmotility and pseudo-obstruction.
- Early recognition and a collaborative approach among healthcare professionals are crucial to manage these issues effectively and improve patient outcomes.
Article Abstract
Gastrointestinal dysfunction in neuromuscular disease is associated with significant morbidity and mortality. It is often underreported despite its prevalence in this cohort. There are a number of issues reported, with gastrointestinal dysmotility and intestinal pseudo-obstruction carrying a poor outcome. We present a case-series of six patients attending a single-centre specialist muscle clinic with a confirmed diagnosis of a neuromuscular disorder (Duchenne muscular dystrophy, mitochondrial disorders, and desmin-related myopathy) and problematic gastrointestinal dysfunction. We advocate prompt recognition and early management, as part of the multi-disciplinary team, to prevent clinical deterioration.
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| http://dx.doi.org/10.1016/j.nmd.2022.05.006 | DOI Listing |
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