Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1056/NEJMicm2117883 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A mitochondria-targeted NIR fluorescence/photoacoustic dual-modality probe for highly sensitive and selective imaging of HClO in vivo.
Spectrochim Acta A Mol Biomol Spectrosc
December 2024
Department of Research & Clinical Laboratory, The Fifth Affiliated Hospital of Guangxi Medical University, The First People's Hospital of Nanning, Nanning 530022, Guangxi, PR China. Electronic address:
Article Synopsis
- Hypochlorous acid (HClO) is a reactive oxygen species produced in mitochondria, and its high levels are associated with various diseases, making its detection crucial in medicine.
- A new dual-modality probe called MB-ClO has been developed, which uses near-infrared fluorescence (NIRF) and photoacoustic (PA) imaging techniques to accurately and sensitively detect HClO in biological systems.
- MB-ClO shows low toxicity and good water solubility, has a fast response time, and has been successfully tested in a mouse model of rheumatoid arthritis, highlighting its potential for biomedical applications.
[Clinical analysis of Tolosa-Hunt syndrome].
Zhonghua Yan Ke Za Zhi
January 2025
Department of Ophthalmology, Tianjin Medical University General Hospital, Tianjin300052, China.
To investigate the clinical features of Tolosa-Hunt syndrome (THS), a type of painful ophthalmoplegia. This was a retrospective case series study. The clinical data of patients diagnosed with painful ophthalmoplegia in the Department of Neurology of Tianjin Medical University General Hospital from January 2019 to December 2022 were continuously collected.
View Article and Find Full Text PDFWutou Decoction: A latest review on molecular mechanisms, clinical studies, quality control, pharmacokinetic studies, pharmacological effects, toxicity, and target prediction.
J Ethnopharmacol
December 2024
State Key Laboratory of Traditional Chinese Medicine Syndrome /The Second Clinical College, Guangzhou University of Chinese Medicine, Guangdong Province 510405, China. Electronic address:
Ethnopharmacological Relevance: Traditional Chinese Medicine (TCM) has great potential and advantages in the treatment of rheumatoid arthritis (RA). Wutou decoction (WTD) was first recorded as a pill in the TCM classical book Synopsis of Prescriptions of the Golden Chamber written by Zhang Zhongjing in the Eastern Han Dynasty (25-220 CE). It has significant therapeutic effects in delaying and reversing RA while improving patients' clinical symptoms, making it the best example of TCM treatment for RA.
View Article and Find Full Text PDFPhytochemical characterization and anti-arthritic potential of green-synthesized CuO nanoparticles derived from the root extract.
Front Pharmacol
December 2024
Department of Pharmacy, University of Agriculture, Faisalabad, Pakistan.
Introduction: Rheumatoid arthritis is an autoimmune disease that mainly causes joint damage. The patient experiences loss of appetite, pain, fever, and fatigue. The present study was designed to phytochemically characterize and evaluate the anti-arthritic activity of green-synthesized copper oxide (CuO) nanoparticles (NPs) using the hydroalcoholic extract of roots in an adjuvant-induced arthritic rat model.
View Article and Find Full Text PDFPsoriasis treatments in the stabilization of atherosclerosis: a systematic review.
Arch Dermatol Res
December 2024
Department of Biomedical Sciences, Tulane School of Medicine, New Orleans, LA, USA.
This systematic review explores the relationship between achieving minimal disease activity in psoriasis and the progression of atherosclerosis. It investigates how biologic therapies and other treatments impact atherosclerosis markers, offering insights into therapeutic strategies. A comprehensive search of PubMed, Embase, and Web of Science was conducted from January 1, 2000, to April 1, 2023, using terms such as psoriasis, psoriatic arthritis, atherosclerosis, biologic therapy, vascular stiffness, carotid intima-media thickness (CIMT), and coronary computed tomography angiography (CCTA).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!