It is controversial whether the cardiac type-2 ryanodine receptor harboring a catecholaminergic polymorphic ventricular tachycardia-associated point mutation is regulated by luminal or cytosolic Ca. This commentary discusses new findings supporting the cytosolic Ca-dependent regulation.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136487 | PMC |
| http://dx.doi.org/10.1085/jgp.202213078 | DOI Listing |
Publication Analysis
Top Keywords
cpvt-linked mutations
4
mutations alter
4
alter ryr2
4
ryr2 regulation
4
regulation cytosolic
4
cytosolic ca2+
4
ca2+ cardiomyocytes?
4
cardiomyocytes? controversial
4
controversial cardiac
4
cardiac type-2
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!