Conditions for extraction, desorption and concentration of specific substances, such as metabolites, and characteristics of their gas-chromatographic division and mass-spectrometric identification have been established. A library for mass-spectra of specific metabolite compounds characteristic of various diseases has been set up. Computer programs for metabolite analysis and for diagnosis were modified. An experimental introduction of chromatographic-mass-spectrometric diagnosis into practice in a number of hospitals and research institutions for prophylactic medical examination of people will make it possible to quickly accumulate statistic data and create the necessary data bank.

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