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High expression of nucleotide-binding oligomerization domain protein 1 correlates with poor prognosis and immune cell infiltration in Glioblastoma Multiforme patients.
Discov Oncol
January 2025
Department of Neurosurgery, China-Japan Union Hospital of Jilin University, Changchun, 130033, Jilin, China.
Nucleotide-binding oligomerization domain protein 1 (NOD1) is one of the innate immune receptors that has been associated with tumorigenesis and abnormally expressed in various cancers. However, the role of NOD1 in Glioblastoma Multiforme (GBM) has not been investigated. We used the Tumor Immune Estimate Resource (TIMER) database to compare the differential expression of NOD1 in various tumors.
View Article and Find Full Text PDFThe cold tolerance of the terrestrial slug, Ambigolimax valentianus.
J Comp Physiol A Neuroethol Sens Neural Behav Physiol
January 2025
Department of Zoology, University of British Columbia, Vancouver, BC, Canada.
Terrestrial molluscs living in temperate and polar environments must contend with cold winter temperatures. However, the physiological mechanisms underlying the survival of terrestrial molluscs in cold environments and the strategies employed by them are poorly understood. Here we investigated the cold tolerance of Ambigolimax valentianus, an invasive, terrestrial slug that has established populations in Japan, Canada, and Europe.
View Article and Find Full Text PDFContinuous Treatment with Tofacitinib but Not Filgotinib Is Effective in Non-Responders with Active Ulcerative Colitis: A Propensity Score-Matching Analysis.
J Clin Med
January 2025
Department of Gastroenterology, Faculty of Medicine, Hyogo Medical University, 1-1 Mukogawa, Nishinomiya 663-8501, Hyogo, Japan.
Few studies have compared the efficacy and safety of Janus kinase (JAK) inhibitors in patients with ulcerative colitis (UC). We compared the real-world effectiveness and safety of tofacitinib (TOF) and filgotinib (FIL) as induction therapy for UC by propensity score-matching analysis. We enrolled 230 patients with active UC who received either TOF (n = 197) or FIL (n = 33) as induction therapy.
View Article and Find Full Text PDFHuman Occupancy Monitoring and Positioning with Speed-Responsive Adaptive Sliding Window Using an Infrared Thermal Array Sensor.
Sensors (Basel)
December 2024
Department of Computer and Information Systems, The University of Aizu, Aizuwakamatsu 965-8580, Fukushima, Japan.
In the current era of advanced IoT technology, human occupancy monitoring and positioning technology is widely used in various scenarios. For example, it can optimize passenger flow in public transportation systems, enhance safety in large shopping malls, and adjust smart home devices based on the location and number of occupants for energy savings. Additionally, in homes requiring special care, it can provide timely assistance.
View Article and Find Full Text PDFHighly Responsive Robotic Prosthetic Hand Control Considering Electrodynamic Delay.
Sensors (Basel)
December 2024
Department of Robotics and Mechatronics, Tokyo Denki University, Tokyo 120-8551, Japan.
As robots become increasingly integrated into human society, the importance of human-machine interfaces continues to grow. This study proposes a faster and more accurate control system for myoelectric prostheses by considering the Electromechanical Delay (EMD), a key characteristic of Electromyography (EMG) signals. Previous studies have focused on systems designed for wrist movements without attempting implementation.
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