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http://dx.doi.org/10.1513/AnnalsATS.202112-1377RL | DOI Listing |
Esophagus
December 2024
Department of Pathology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China.
Background: Esophageal cancer is highly prevalent in China, predominantly represented by squamous cell carcinoma. This retrospective study sought to evaluate the diagnostic efficacy of four staining protocols in identifying early stage esophageal squamous cell carcinoma (ESCC).
Methods: A consecutive series of ninety biopsy samples of esophageal mucosa, collected retrospectively from March 2016 to December 2019, were obtained at Beijing Chao-Yang Hospital, a tertiary care facility in Beijing, China.
Hypervirulent Klebsiella pneumoniae (hvKp) can cause life-threatening infections in healthy community members. HvKp infections often involve multiple sites, some of which are unusual for classical K. pneumoniae (cKp) infections, such as the central nervous system, eyes, and fascia.
View Article and Find Full Text PDFJMIR Form Res
December 2024
Department of Dermatology and Allergy, Technical University of Munich, Munich, Germany.
Background: The rapid development of large language models (LLMs) such as OpenAI's ChatGPT has significantly impacted medical research and education. These models have shown potential in fields ranging from radiological imaging interpretation to medical licensing examination assistance. Recently, LLMs have been enhanced with image recognition capabilities.
View Article and Find Full Text PDFMicrobiol Spectr
December 2024
Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, Kentucky, USA.
Unlabelled: The BioFire FilmArray meningitis/encephalitis panel (MEP) was brought to the University of Kentucky in 2016 to aid in the identification of community-acquired meningitis and encephalitis (ME). This panel has shown variable performance with some institutions showing high sensitivity and specificity for many pathogens but others seeing false positives during clinical use. We evaluated the panel's performance using retrospective chart review of patients at the University of Kentucky from October 2016 to September 2022, including 7,551 MEP results.
View Article and Find Full Text PDFEur J Neurol
January 2025
Department of Neurology, Martin-Luther-University of Halle-Wittenberg, Halle (Saale), Germany.
Background: We aimed to investigate the prognostic role of β-synuclein in comparison to that of neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) for predicting functional outcome after acute ischemic stroke (AIS).
Methods: We measured serum concentrations of β-synuclein, NfL and GFAP 24 h after hospital admission in 213 consecutive patients with moderate-to-severe AIS. We investigated the association between serum biomarkers and radiological/clinical characteristics, 3-months mortality and functional outcome on the modified Rankin Scale (mRS).
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