Two new nor-triterpenoids ganodrenol A (), B (), and a new natural product ganodrenol C (), along with three known nor-triterpenoids (-) were isolated from the fruiting bodies of The chemical structures of these isolates were determined by 1 D and 2 D NMR, HRESIMS, and X-ray crystallography analysis. The inhibitory effects of isolated triterpenoids (-) against FAAH were evaluated by an in assay, and compound showed an inhibition rate of 70.27%. In addition, the cytotoxic effect of compounds (-) was evaluated against LOVO, MCF-7, and RAW264.7 cells, which displayed no significant cytotoxicity.

Download full-text PDF

Source
http://dx.doi.org/10.1080/14786419.2022.2078817DOI Listing

Publication Analysis

Top Keywords

fruiting bodies
8
nor-triterpenoids fruiting
4
bodies inhibitory
4
inhibitory activity
4
activity faah
4
faah nor-triterpenoids
4
nor-triterpenoids ganodrenol
4
ganodrenol natural
4
natural product
4
product ganodrenol
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!