We demonstrated that the activity gap between metal-organic frameworks (Fe) and horseradish peroxidase could be bridged by simulating the binding-pocket structure and adding active centers. This customized structure promoted the activation and enrichment of substrates, and addition of gold nanoparticles led to activity superposition and synergistic enhancement.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/d2cc01634f | DOI Listing |
Publication Analysis
Top Keywords
binding-pocket structure
8
simulation design
4
design binding-pocket
4
structure natural
4
natural enzymes
4
enzymes mofs
4
mofs enhanced
4
enhanced catalytic
4
catalytic activity
4
activity demonstrated
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!