For individuals with end stage kidney disease (ESKD), kidney transplantation is associated with reduced morbidity, mortality, and decreased health care costs. African Americans have higher rates of end stage kidney disease (ESKD) and reduced access to transplantation compared to their White counterparts. One way to improve access to transplantation is by increasing the number of living donors. Currently, African Americans with ESKD comprise 31% of the transplant waitlist and only 8% of the living kidney donors. Often individuals with ESKD are hesitant to inform loved ones about living donation out of concerns that their donors may feel pressured or may be harmed by donation. Even when patients discuss donation with loved ones, these potential donors may not seek information from their physicians. As an important first step, we provide general information about living donation to primary care physicians for their African Americans patients with ESKD and potential African American donors.
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http://dx.doi.org/10.1016/j.jnma.2022.05.001 | DOI Listing |
Hum Brain Mapp
February 2025
Department of Neurology, Washington University in St. Louis, St. Louis, Missouri, USA.
Neurodegeneration is presumed to be the pathological process measure most proximal to clinical symptom onset in Alzheimer Disease (AD). Structural MRI is routinely collected in research and clinical trial settings. Several quantitative MRI-based measures of atrophy have been proposed, but their low correspondence with each other has been previously documented.
View Article and Find Full Text PDFClin Pharmacol Ther
January 2025
Department of Pharmacology, Center for Pharmacogenomics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Clopidogrel, an anti-platelet drug, is used to prevent thrombosis after percutaneous coronary intervention. Clopidogrel resistance results in recurring ischemic events, with African Americans (AA) suffering disproportionately. The aim of this study was to discover novel biomarkers of clopidogrel resistance in African Americans using genome and transcriptome data.
View Article and Find Full Text PDFAim: To understand how Black or African American women living with HIV (WLH) experience different types of stigma in their daily lives.
Design: Secondary analysis of quantitative and qualitative data from a recent clinical trial in Baltimore, Maryland.
Methods: Quantitative data were collected in the baseline survey, and qualitative data were gathered during 6-month follow-up focus group and individual interviews.
AIDS Care
January 2025
Westat, Rockville, MD, USA.
Transgender youth are disproportionately affected by HIV, particularly minoritized youth in the US south. To understand HIV service use among transgender youth, we interviewed 25 young racial and ethnic minority clients of four southern community-based HIV service organizations (CBOs), and CBO staff ( = 12), about service access and use. Participants were assigned male at birth and identified as female ( = 8), transgender ( = 11) or gender-fluid or nonbinary ( = 6).
View Article and Find Full Text PDFThe Arabian Peninsula is considered the initial site of historic human migration out of Africa. The modern-day indigenous Arabians are believed to be the descendants who remained from the ancient split of the migrants into Eurasia. Here, we investigated how the population history and cultural practices such as endogamy have shaped the genetic variation of the Saudi Arabians.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!