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http://dx.doi.org/10.4088/PCC.21cr03032DOI Listing

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Introduction: Wernicke encephalopathy is a clinical diagnosis that requires a high degree of clinical suspicion to recognize. We report a case of a pregnant patient developing Wernicke encephalopathy in the setting of severe hyperemesis gravidarum.

Case Report: The patient was a 22-year-old female 13 weeks pregnant presenting to the emergency department (ED) with neurological deficits after several weeks of hyperemesis gravidarum requiring hospitalization.

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A pregnant woman was brought to the emergency department looking starved and neglected. She was diagnosed with sepsis and started on intravenous antibiotics. She was also disoriented and hypernatremic.

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Wernicke's encephalopathy, the acute phase of Wernicke-Korsakoff syndrome, is characterised as a triad of altered mental status, ocular signs and ataxia. Our patient presented with hyperemesis gravidarum, which is a rare aetiology of Wernicke's encephalopathy. The patient did not have any oculomotor abnormalities, which are more common and classically described in Wernicke's triad.

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Consciousness disturbance in patients with chronic kidney disease: Rare but potentially treatable complication. Clinical and neuroradiological review.

Behav Brain Res

December 2024

Radiology and Neuroradiology Unit, Department of Imaging, Radiation Therapy and Hematology, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Largo A. Gemelli, 1, Rome 00168, Italy.

Article Synopsis
  • In patients with chronic kidney disease undergoing dialysis, brain complications like Posterior Reversible Encephalopathy Syndrome and uremic encephalopathy can develop, with their potential reversibility depending on early detection and treatment.
  • Neurological symptoms can range widely from mild consciousness disturbances to coma, and imaging plays a crucial role in diagnosing the specific underlying issues.
  • Complications linked to dialysis include Dialysis Disequilibrium Syndrome and Osmotic Demyelination Syndrome, each showing unique imaging patterns, but accurate diagnosis often requires a detailed clinical history and lab results due to occasionally overlapping features.
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