AI Article Synopsis
- The study investigates the sleep issues faced by memory clinic patients with subjective cognitive decline (SCD) and how these problems relate to cognition, mental health, and biomarkers.
- Out of 308 subjects, 64% reported sleep problems, with 35% indicating sleep apnea and 53% suffering from poor sleep quality.
- The findings suggest that enhancing sleep quality could be a potential treatment avenue for alleviating cognitive complaints in SCD patients, as those with sleep problems showed higher levels of depression and anxiety.
Article Abstract
We aim to investigate the frequency and type of sleep problems in memory clinic patients with subjective cognitive decline (SCD) and their association with cognition, mental health, brain magnetic resonance imaging (MRI), and cerebrospinal fluid (CSF) biomarkers. Three hundred eight subjects (65 ± 8 years, 44% female) were selected from the Subjective Cognitive Impairment Cohort (SCIENCe) project. All subjects answered two sleep questionnaires, Berlin Questionnaire (sleep apnea) and Pittsburgh Sleep Quality Index (sleep quality) and underwent a standardized memory clinic work-up. One hundred ninety-eight (64%) subjects reported sleep problems, based on 107 (35%) positive screenings on sleep apnea and 162 (53%) on poor sleep quality. Subjects with sleep problems reported more severe depressive symptoms, more anxiety, and more severe SCD. Cognitive tests, MRI, and CSF biomarkers did not differ between groups. Our results suggest that improvement of sleep quality and behaviors are potential leads for treatment in many subjects with SCD to relieve the experienced cognitive complaints.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107682 | PMC |
| http://dx.doi.org/10.1002/dad2.12287 | DOI Listing |
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