AI Article Synopsis
- The use of antibiotic prophylaxis in orthopedic surgery has remained largely unchanged for nearly 50 years, despite the rise of resistant bacterial strains.
- A study examined positive cultures from hip and knee joint replacement and trauma surgeries, revealing increased resistance to oxacillin and a rise in Gram-negative bacteria.
- The findings indicate that the current standard of using cephalosporins for prophylaxis is inadequate, suggesting a need to reevaluate antibiotic practices in surgery.
Article Abstract
Introduction: The current practice of antibiotic prophylaxis in orthopedic surgery has existed almost 50 years yet little changes have been made. The incidence of methicillin resistant and multi-drug resistant Gram-negative bacteria is growing.
Methods: We studied the positive cultures after primary hip and knee joint replacement and trauma surgery at our department.
Results: Our investigation substantiates the current reports of an increase in oxacillin resistance of and an increase in incidence of Gram-negative bacteria. The standard use of cephalosporins for prophylaxis does not provide the necessary protection that it used to. We suggest that the recommendations and practice of antibiotic prophylaxis should be reconsidered.
Level Of Evidence: Level III - retrospective cohort study.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117254 | PMC |
| http://dx.doi.org/10.1016/j.jor.2022.05.008 | DOI Listing |
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