AI Article Synopsis
- Ascorbic acid (vitamin C) plays a crucial role in many biological processes, but its specific functions inside cells haven't been fully studied.
- Researchers developed a new analytical method using HPLC-ESI-MS/MS that can detect very low levels of ascorbic acid (as low as 1 picogram).
- This advancement allows for better understanding of how ascorbic acid behaves and functions within cells.
Article Abstract
Ascorbic acid is involved in a variety of biological events. Nevertheless, its detailed intracellular behavior remains unexplored due to a lack of sensitive analytical methods. Here we report a method using HPLC-ESI-MS/MS achieving the lowest detection limit ever reported (1 pg), to provide mechanistic insight into the intracellular ascorbic acid physiology.
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| http://dx.doi.org/10.1039/d1an02160e | DOI Listing |
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