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Adverse cardiovascular events and cardiac imaging findings in patients on immune checkpoint inhibitors.
PLoS One
December 2024
Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America.
Background: There is an urgent need to better understand the diverse presentations, risk factors, and outcomes of immune checkpoint inhibitor (ICI)-associated cardiovascular toxicity. There remains a lack of consensus surrounding cardiovascular screening, risk stratification, and clinical decision-making in patients receiving ICIs.
Methods: We conducted a single center retrospective cohort study including 2165 cancer patients treated with ICIs between 2013 and 2020.
The negative effects of long COVID-19 on cardiovascular health and implications for the presurgical examination.
J Osteopath Med
October 2024
Blue Ridge Health Family Medicine, Sylva, NC, USA.
Article Synopsis
- The emergence of SARS-CoV-2 in 2019 led to widespread health challenges, revealing gaps in understanding the long-term effects of COVID-19, particularly on cardiovascular health.
- Long COVID-19 can cause serious cardiovascular issues such as chest pain, arrhythmias, heart failure, and even sudden cardiac death, making it crucial for healthcare providers to assess these risks during preoperative evaluations for affected patients.
- This literature review aims to enhance knowledge about the cardiovascular impacts of long COVID-19 and emphasize the need for thorough presurgical cardiac clearance amidst limited current evidence.
Myocarditis and Pericarditis are Temporally Associated with BNT162b2 COVID-19 Vaccine in Adolescents: A Systematic Review and Meta-analysis.
Pediatr Cardiol
October 2024
Graduate School of Urban Public Health, University of Seoul, 163 Seoulsiripdae-ro, Dongdaemun-gu, Seoul, 02504, Republic of Korea.
The incidence of myocarditis and pericarditis has been documented in adolescents after COVID-19 vaccinations. This study aims to assess the risk of myopericarditis in adolescents following COVID-19 vaccination, using a meta-analysis of the published cases. We performed a comprehensive literature search of the following databases on July 5, 2023: MEDLINE, EMBASE, PubMed, and the Cochrane Library.
View Article and Find Full Text PDFAdult-onset Still's disease masquerading as acute coronary syndrome: a case report and review of the literature.
J Med Case Rep
October 2024
Division of Infectious Diseases and Epidemiology, Department of Medicine, Penn State Health Milton S. Hershey Medical Center, 500 University Drive, Hershey, PA, 17033, USA.
Article Synopsis
- Adult-onset Still's disease is a rare inflammatory condition that can cause symptoms like fevers and myopericarditis, as seen in a young man who developed these after a respiratory infection.
- The patient had significant medical issues, including high fever, chest pain, and was eventually diagnosed after thorough testing; he responded well to steroids but experienced side effects before achieving remission with tocilizumab.
- Early recognition of this disease is essential for effective treatment, as steroids are the primary option despite their risks, while newer biologics like tocilizumab offer benefits but can be expensive.
Cardiovascular events following coronavirus disease 2019 vaccination in adults: a nationwide Swedish study.
Eur Heart J
January 2025
School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, BOX 414, 40 530 Gothenburg, Sweden.
Article Synopsis
- The study investigates the cardiovascular effects of COVID-19 mRNA vaccination in over 8 million Swedish adults, focusing on risks for myocarditis, pericarditis, dysrhythmias, heart failure, myocardial infarction, and cerebrovascular events.
- Results indicate that while there is a temporary increase in risks for myocarditis and extrasystoles shortly after vaccination, overall cardiovascular risks significantly decrease after full vaccination, particularly after the third dose.
- The findings highlight the importance of vaccination in reducing severe cardiovascular complications associated with COVID-19, validating its protective benefits despite some rare adverse events.
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