Restoring type VII collagen in skin.

Med

St John's Institute of Dermatology, King's College London (Guy's Campus), London SE1 9RT, UK. Electronic address:

Published: May 2022

New therapeutic hope is emerging for people with the rare inherited blistering skin disease recessive dystrophic epidermolysis bullosa (RDEB). Gurevich et al. have reported early-phase clinical trial data evaluating a topical herpes simplex virus 1 vector to restore missing type VII collagen in RDEB skin and heal wounds.

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http://dx.doi.org/10.1016/j.medj.2022.04.008DOI Listing

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