Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.bbi.2022.05.008 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Mesenchymal stem cell therapy in eosinophilic granulomatosis with polyangiitis-related lower limb gangrene: a case report.
Stem Cell Res Ther
September 2024
Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University, No. 45, Changchun Street, Beijing, 100053, China.
Article Synopsis
- Eosinophilic granulomatosis with polyangiitis (EGPA) is a serious systemic vasculitis characterized by high eosinophil levels and various symptoms, requiring high-dose glucocorticoid treatment, though this isn't always effective.
- A case study of an 11-year-old patient at risk of amputation due to severe necrotizing vasculitis utilized mesenchymal stem cell therapy, which included umbilical cord and placenta-derived cells.
- After four months of treatment, the patient experienced improved eosinophil levels, restored blood flow, and significant healing of foot ulcerations, suggesting stem cell therapy could be a valuable alternative for treatment-resistant EGPA.
MA-mediated upregulation of lncRNA TUG1 in liver cancer cells regulates the antitumor response of CD8 T cells and phagocytosis of macrophages.
Adv Sci (Weinh)
September 2024
Laboratory of Immunology and Inflammation, Department of Biotechnology, School of Life Sciences and Biopharmaceutics, Guangdong Provincial Key Laboratory of Advanced Drug Delivery, Guangdong Provincial Engineering Center of Topical Precise Drug Delivery System, Guangdong Pharmaceutical University, Guangzhou, 51006, China.
Tumor immune evasion relies on the crosstalk between tumor cells and adaptive/innate immune cells. Immune checkpoints play critical roles in the crosstalk, and immune checkpoint inhibitors have achieved promising clinical effects. The long non-coding RNA taurine-upregulated gene 1 (TUG1) is upregulated in hepatocellular carcinoma (HCC).
View Article and Find Full Text PDFMatrisome and Immune Pathways Contribute to Extreme Vascular Outcomes in Williams-Beuren Syndrome.
J Am Heart Assoc
February 2024
National Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD.
Background: Supravalvar aortic stenosis (SVAS) is a characteristic feature of Williams-Beuren syndrome (WBS). Its severity varies: ~20% of people with Williams-Beuren syndrome have SVAS requiring surgical intervention, whereas ~35% have no appreciable SVAS. The remaining individuals have SVAS of intermediate severity.
View Article and Find Full Text PDFMast cells link immune sensing to antigen-avoidance behaviour.
Nature
August 2023
Division for Cellular Immunology, German Cancer Research Center, Heidelberg, Germany.
The physiological functions of mast cells remain largely an enigma. In the context of barrier damage, mast cells are integrated in type 2 immunity and, together with immunoglobulin E (IgE), promote allergic diseases. Allergic symptoms may, however, facilitate expulsion of allergens, toxins and parasites and trigger future antigen avoidance.
View Article and Find Full Text PDFVirus-associated fungal infections and lost immune resistance.
Trends Immunol
April 2023
Calvin, Phoebe, and Joan Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada; Department of Critical Care Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. Electronic address:
Invasive fungal infections are an increasing threat to human health. Of recent concern is the emergence of influenza- or SARS-CoV-2-virus-associated invasive fungal infections. Understanding acquired susceptibilities to fungi requires consideration of the collective and newly explored roles of adaptive, innate, and natural immunity.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!