AI Article Synopsis
- * The study introduces a liquid-crystal (LC)-based assay that rapidly detects AFB1 in food using small droplets created through a solvent evaporation method, yielding a unique four-leaf clover appearance.
- * This detection method requires only 1 µL of sample and can identify AFB1 at concentrations as low as 10 pg/mL, making it a simple, sensitive, and portable option for on-field testing without the need for bulky equipment.
Article Abstract
Aflatoxin B1 (AFB1) is a common food mycotoxin that can cause various diseases. Therefore, reliable detection methods are required to ensure food safety against mycotoxins. In this study, we design a liquid-crystal (LC)-based assay for rapid detection of AFB1 in food samples. The surface-anchored LC droplets on glass (5CB) are obtained via a solvent evaporation method. The 5CB displays a four-leaf clover appearance that corresponds to an escape-radial configuration in a mixture of CTAB and AFB1 aptamer. Interestingly, they adopt a radial configuration in the mixture of CTAB, AFB1, and its aptamer. Using this approach, AFB1 can be detected using only 1 µL of the aqueous solution with a minimum detection concentration of 10 pg/mL. This LC-based sensing platform provides simple operation, remarkable sensitivity, high selectivity, low cost, and excellent portability without the use of any bulky instrument, which is very promising in rapid on-field detection of mycotoxins.
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| http://dx.doi.org/10.1016/j.foodchem.2022.133202 | DOI Listing |
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