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Editorial for "Significance of Cerebral Small-Vessel Disease on Perihematomal Edema Progress in Patients With Hypertensive Intracerebral Hemorrhage".
J Magn Reson Imaging
January 2023
Departments of Neurology, Anesthesia/Critical Care Medicine, Neurosurgery, and General Internal Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Commentary: Perihematomal Edema and Clinical Outcome After Intracerebral Hemorrhage; A Systematic Review and Meta-analysis.
Neurocrit Care
October 2022
Department of Neurological Surgery, University of Virginia Health System, Charlottesville, VA, USA.
Brain tissue iron quantification by MRI in intracerebral hemorrhage: Current translational evidence and pitfalls.
J Cereb Blood Flow Metab
March 2019
2 Department of Neurosurgery, University of Michigan, Ann Arbor, MI, USA.
Intracerebral hemorrhage (ICH) is a common subtype of hemorrhagic stroke with devastating consequences with no specific treatment. There is, however, substantial evidence for iron-mediated neurotoxicity in animal ICH models. Non-invasive quantification of the peri-hematomal tissue iron based on MRI has shown some promise in animal models and is being validated for clinical translation.
View Article and Find Full Text PDFUrokinase, a promising candidate for fibrinolytic therapy for intracerebral hemorrhage.
J Neurosurg
February 2017
Department of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing; and.
OBJECTIVE Intracerebral hemorrhage (ICH) is associated with a high rate of mortality and severe disability, while fibrinolysis for ICH evacuation is a possible treatment. However, reported adverse effects can counteract the benefits of fibrinolysis and limit the use of tissue-type plasminogen activator (tPA). Identifying appropriate fibrinolytics is still needed.
View Article and Find Full Text PDFBlood pressure lowering and acute perihematomal brain edema after intracerebral hemorrhage.
Stroke
May 2014
From the Department of Neurosurgery, University of Michigan, Ann Arbor.
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