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The impacts of the COVID-19 pandemic on Australia's myasthenia gravis patients: A self-reported survey study.
Neurol Sci
December 2024
Eastern Health Clinical School, Monash University, Box Hill Hospital, Melbourne, VIC, 3128, Australia.
Introduction/aims: Previous studies have demonstrated high morbidity and mortality in patients with myasthenia gravis (MG) who acquired COVID-19. We aimed to identify the impact of the pandemic on MG disease control, treatment and quality of life.
Methods: A prospective observational cohort study was conducted to identify the impact of the COVID-19 pandemic on Australian patients with MG.
Longitudinal analysis highlights structural changes in grey- and white-matter within military personnel exposed to blast.
Brain Inj
December 2024
Centre for Neuroscience Studies, Queen's University, Kingston, Ontario, Canada.
Objective: The purpose of this study was to determine whether gray matter volume and diffusion-based metrics in associated white matter changed in breachers who had neuroimaging performed at two timepoints. A secondary purpose was to compare these changes in a group who had a one-year interval between their imaging timepoints to a group that had a two-year interval between imaging.
Methods: Between timepoints, clusters with significantly different gray matter volume were used as seeds for reconstruction of associated structural networks using diffusion metrics.
Advancing Thalamic Nuclei Segmentation: The Impact of Compressed Sensing on MRI Processing.
Hum Brain Mapp
December 2024
Center for Mind/Brain Sciences-CIMeC, University of Trento, Rovereto, Italy.
The thalamus is a collection of gray matter nuclei that play a crucial role in sensorimotor processing and modulation of cortical activity. Characterizing thalamic nuclei non-invasively with structural MRI is particularly relevant for patient populations with Parkinson's disease, epilepsy, dementia, and schizophrenia. However, severe head motion in these populations poses a significant challenge for in vivo mapping of thalamic nuclei.
View Article and Find Full Text PDFPredicting recovery in patients with mild traumatic brain injury and a normal CT using serum biomarkers and diffusion tensor imaging (CENTER-TBI): an observational cohort study.
EClinicalMedicine
September 2024
Department of Medicine, University of Cambridge, Cambridge, UK.
Background: Even patients with normal computed tomography (CT) head imaging may experience persistent symptoms for months to years after mild traumatic brain injury (mTBI). There is currently no good way to predict recovery and triage patients who may benefit from early follow-up and targeted intervention. We aimed to assess if existing prognostic models can be improved by serum biomarkers or diffusion tensor imaging metrics (DTI) from MRI, and if serum biomarkers can identify patients for DTI.
View Article and Find Full Text PDFDevelopment and Validation of a Yoga-Based Intervention for Speech Dysfunction and Speech Difficulties Among Patients With Parkinson's Disease.
Cureus
November 2024
Integrative Medicine, Division of Yoga, Ministry of Ayush, Central Research Institute of Yoga and Naturopathy (CRIYN), Nagamangala, IND.
Introduction Parkinson's disease (PD) is primarily thought to be brought on by the death of dopaminergic neurons in the substantia nigra pars compacta of the basal ganglia. Communication difficulties are a common symptom of PD, affecting both motor speech and language systems. These challenges significantly impact the quality of life by reducing participation in communication, leading to social withdrawal, and increasing the risk of social isolation and stigma among individuals with PD.
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